Arch Dermatol
 1946
DOI: 10.1001/archderm.1946.01510300042009
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Diffusion of Water Through Dead Plantar, Palmar and Torsal Human Skin and Through Toe Nails

George E. Burch1
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Cited by 65 publications

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“…(Tregear, 1966) Tregear's work, alongside Burch et al, noted that recently dead skin does not affect the permeability of the skin, a major development in our ability to use excised skin in diffusion cells. This was shown experimentally for both water and tri-n-butyl phosphate (Burch and Winsor, 1946;Bronaugh and Stewart, 1984). Thus, excised skin can be used for measuring permeability.…”
Section: History Of Permeationmentioning
confidence: 75%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…(Tregear, 1966) Tregear's work, alongside Burch et al, noted that recently dead skin does not affect the permeability of the skin, a major development in our ability to use excised skin in diffusion cells. This was shown experimentally for both water and tri-n-butyl phosphate (Burch and Winsor, 1946;Bronaugh and Stewart, 1984). Thus, excised skin can be used for measuring permeability.…”
Section: History Of Permeationmentioning
confidence: 75%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The nail plate hydration plays a significant role in permeability of the nail plate. Water flux in fully hydrated nail plate was found to be 12.6±5.6 mg/cm 2 /h or 126±56 g/m 2 /h (permeability coefficient of (16.5±5.9)×10 −3 cm/h) by Walters et al., which is almost 6.5 times the value of 2.5 mg/cm 2 /h determined by Burch and Windson in dry nails . This is attributed to the fact that hydrated nail plate holds 0.3‐0.5 g of water/g of dry nail weight .…”
Section: Permeability Of Human Nail Platementioning
confidence: 83%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Working on diseased nails (eczema, psoriasis and onychomycosis), Krönauer estimated a mean TOWL of 12.9 g/m 2 /h (14). Burch and Windsor (17) found lower values but also important flux variations (1.6–53 g/m 2 /h) depending on the temperature and humidity. A standard TOWL calibration, not currently available, would make such a comparison more meaningful.…”
Section: Discussionmentioning
confidence: 98%
“…Few studies have documented human nail permeability (14)(15)(16)(17)(18)(19)(20)(21). Germann et al first described tape stripping on a nail to remove nail corneocytes (22).…”
mentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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