Diffuse Left Ventricular Myocardial Calcification in the Setting of Sepsis on CT Imaging

Simonson, Stephanie; Miller, Wallace T.; Perl, Alexander E.; Torigian, Drew A.

doi:10.1097/rti.0b013e31806ad289

Cited by 20 publications

(25 citation statements)

References 8 publications

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“…van Kruijsdijk et al 2 Schellhammer et al 3 Simonson et al 4 Lapatto-Reiniluoto et al 5 Our patient Table. Summary of reported cases in the literature with myocardial calcification with sepsis. [2][3][4][5] Abbreviations: ECG = electrocardiography; ECHO = echocardiogram; EF = ejection fraction; LV = left ventricular; N/A = not available. * Same for all five patients.…”

Section: Discussionmentioning

confidence: 90%

Acute / Subacute Development of Diffuse Left Ventricular Myocardial Calcification in Sepsis Associated with High Mortality

Chan¹,

Tsang²,

Hon³

et al. 2016

Hong Kong J Radiol

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Diffuse myocardial calcification is very rare and can be either dystrophic or metastatic. Acute / subacute development of diffuse myocardial calcification of the left ventricle in an acute setting has been rarely reported but is found in a septic patient in our case. We believe that the cause of myocardial calcification is likely multifactorial. In particular, high-dose inotropic support is likely a contributing cause of calcification due to cardiomyopathy. More importantly, it is associated with very poor cardiac function and high mortality.

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Section: Discussionmentioning

confidence: 90%

Acute / Subacute Development of Diffuse Left Ventricular Myocardial Calcification in Sepsis Associated with High Mortality

Chan¹,

Tsang²,

Hon³

et al. 2016

Hong Kong J Radiol

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“…It develops rapidly from days to months in areas of myocardial necrosis, hemorrhage, or fibrosis [3,4]. It is also reported in patients with severe sepsis and septic shock [5][6][7][8][9][10]. Sepsis itself causes cardiomyopathy described as acute left ventricular wall dilation and decrease in ejection fraction.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Calcification Following Severe Sepsis: A Case Report and Review of the Literature

Karakurt¹

2014

J Anesth Clin Res

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There are two types of myocardial calcification: metastatic calcification that is encountered in chronic renal disease patients and dystrophic calcification which develops in injured myocardium. Myocardial infarction, trauma, surgery and myocarditis are the most commonly faced reasons for dystrophic calcification. Here we present a rare case of a patient in whom myocardial calcification was diagnosed after severe sepsis.

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“…Myocardial calcification has been rarely reported in septic shock, despite the high incidence of the later [6][7][8][9][10][11]. Myocardial calcification has been also described in acute myocarditis [12,13].…”

Section: Discussionmentioning

confidence: 99%

Reversible Myocardial Calcification Following Severe Leptospirosis Complicated With Rhabdomyolysis-Induced Acute Kidney Injury and Magnesium-Wasting Nephropathy

Zakout

2013

J Med Cases

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We present a patient with leptospirosis infection who presented septic shock with multiple-organ dysfunction syndrome, severe rhabdomyolysis and acute myocarditis. He developed biphasic blood calcium pattern with hypocalcemia in the oliguric phase followed by hypercalcemia during the recovery diuretic phase in the context of rhabdomyolysis and oliguric acute kidney injury. Meanwhile, he developed an extensive calcification of the myocardium. Severe renal magnesium wasting was observed during the convalescence phase. Follow-up showed progressive resorption and later almost total disappearance of the calcific deposits in the heart by the 18th month after discharge. Renal magnesium wasting decreased gradually, but yet persisted beyond the 18th and was normalized only by the 36th month after discharge. We discuss the pathophysiologic mechanisms involved in the myocardial calcification and renal magnesium wasting and suggest a possibility of a contributing role of magnesium renal wasting in mobilization of calcium deposits out of myocardium.

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Diffuse Left Ventricular Myocardial Calcification in the Setting of Sepsis on CT Imaging

Abstract: We describe a 58-year-old man with acute lymphoblastic leukemia who developed diffuse left ventricular myocardial calcification during an episode of sepsis seen at computed tomographic imaging.

Cited by 20 publications

References 8 publications

Acute / Subacute Development of Diffuse Left Ventricular Myocardial Calcification in Sepsis Associated with High Mortality

Acute / Subacute Development of Diffuse Left Ventricular Myocardial Calcification in Sepsis Associated with High Mortality

Cardiac Calcification Following Severe Sepsis: A Case Report and Review of the Literature

Reversible Myocardial Calcification Following Severe Leptospirosis Complicated With Rhabdomyolysis-Induced Acute Kidney Injury and Magnesium-Wasting Nephropathy

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