Diffuse Dermal Angiomatosis

Diffuse dermal angiomatosis of the breast

“…10 Severe atherosclerosis can manifest as peripheral arterial disease with occlusion of major vasculature, causing diminished blood flow in the legs and breasts of women. 1,9,11,12,17,21,23 As DDA can be an indicator of severe atherosclerosis, patients with relevant risk factors should undergo appropriate workup.…”

“…6,7,9,11,24 Conservative treatment with isotretinoin, oral corticosteroids, or pentoxifylline/aspirin has shown variable degrees of success. [4][5][6]9,11,13,15,16,19,21,23,26 Spontaneous resolution has also been reported. 9 Similar to case reports by McLaughlin et al 4 and Song et al 27 our patient had no history of ischemia or vascular disorders.…”

Diffuse dermal angiomatosis of the breast

“…10 Severe atherosclerosis can manifest as peripheral arterial disease with occlusion of major vasculature, causing diminished blood flow in the legs and breasts of women. 1,9,11,12,17,21,23 As DDA can be an indicator of severe atherosclerosis, patients with relevant risk factors should undergo appropriate workup.…”

“…6,7,9,11,24 Conservative treatment with isotretinoin, oral corticosteroids, or pentoxifylline/aspirin has shown variable degrees of success. [4][5][6]9,11,13,15,16,19,21,23,26 Spontaneous resolution has also been reported. 9 Similar to case reports by McLaughlin et al 4 and Song et al 27 our patient had no history of ischemia or vascular disorders.…”

Diffuse Dermal Angiomatosis of the Breast: A Distinct Entity in the Spectrum of Cutaneous Reactive Angiomatoses – Clinicopathologic Study of Two Cases and Comprehensive Review of the Literature

“…A wide spectrum of predisposing comorbid conditions have been associated with DDA in other body parts than the breast, such as advanced atherosclerotic vascular disease [ 6 , 7 , 8 , 9 , 10 ], iatrogenic arteriovenous fistula in the setting of chronic hemodialysis [ 11 , 12 ], monoclonal gammopathy [ 13 , 14 ], and the administration of trabectedin and pegfilgrastim in the context of liposarcoma in 1 case [ 15 ]. Cardiovascular risk factors, atherosclerotic vascular disease, and monoclonal gammopathy have also been described in association with DDAB.…”

Diffuse Dermal Angiomatosis: A Clue to the Diagnosis of Atherosclerotic Vascular Disease

“…In addition, all reported patients had multiple atherosclerotic comorbidities such as hypertension, dyslipidemia, diabetes mellitus, chronic kidney disease and heavy smoking. Most of them had undergone revascularization procedures, and all lesions rapidly healed shortly after the procedures [ 2 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. However, one reported patient who received conservative medical therapy, which included oral prednisolone and colchicine, died from severe sepsis.…”

Diffuse dermal angiomatosis of the breast

“…10 Severe atherosclerosis can manifest as peripheral arterial disease with occlusion of major vasculature, causing diminished blood flow in the legs and breasts of women. 1,9,11,12,17,21,23 As DDA can be an indicator of severe atherosclerosis, patients with relevant risk factors should undergo appropriate workup.…”

“…6,7,9,11,24 Conservative treatment with isotretinoin, oral corticosteroids, or pentoxifylline/aspirin has shown variable degrees of success. [4][5][6]9,11,13,15,16,19,21,23,26 Spontaneous resolution has also been reported. 9 Similar to case reports by McLaughlin et al 4 and Song et al 27 our patient had no history of ischemia or vascular disorders.…”

Diffuse Dermal Angiomatosis of the Breast: A Distinct Entity in the Spectrum of Cutaneous Reactive Angiomatoses – Clinicopathologic Study of Two Cases and Comprehensive Review of the Literature

“…A wide spectrum of predisposing comorbid conditions have been associated with DDA in other body parts than the breast, such as advanced atherosclerotic vascular disease [ 6 , 7 , 8 , 9 , 10 ], iatrogenic arteriovenous fistula in the setting of chronic hemodialysis [ 11 , 12 ], monoclonal gammopathy [ 13 , 14 ], and the administration of trabectedin and pegfilgrastim in the context of liposarcoma in 1 case [ 15 ]. Cardiovascular risk factors, atherosclerotic vascular disease, and monoclonal gammopathy have also been described in association with DDAB.…”

Diffuse Dermal Angiomatosis: A Clue to the Diagnosis of Atherosclerotic Vascular Disease

“…In addition, all reported patients had multiple atherosclerotic comorbidities such as hypertension, dyslipidemia, diabetes mellitus, chronic kidney disease and heavy smoking. Most of them had undergone revascularization procedures, and all lesions rapidly healed shortly after the procedures [ 2 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. However, one reported patient who received conservative medical therapy, which included oral prednisolone and colchicine, died from severe sepsis.…”

Diffuse dermal angiomatosis of the breast

“…10 Severe atherosclerosis can manifest as peripheral arterial disease with occlusion of major vasculature, causing diminished blood flow in the legs and breasts of women. 1,9,11,12,17,21,23 As DDA can be an indicator of severe atherosclerosis, patients with relevant risk factors should undergo appropriate workup.…”

“…6,7,9,11,24 Conservative treatment with isotretinoin, oral corticosteroids, or pentoxifylline/aspirin has shown variable degrees of success. [4][5][6]9,11,13,15,16,19,21,23,26 Spontaneous resolution has also been reported. 9 Similar to case reports by McLaughlin et al 4 and Song et al 27 our patient had no history of ischemia or vascular disorders.…”

Diffuse Dermal Angiomatosis of the Breast: A Distinct Entity in the Spectrum of Cutaneous Reactive Angiomatoses – Clinicopathologic Study of Two Cases and Comprehensive Review of the Literature

“…A wide spectrum of predisposing comorbid conditions have been associated with DDA in other body parts than the breast, such as advanced atherosclerotic vascular disease [ 6 , 7 , 8 , 9 , 10 ], iatrogenic arteriovenous fistula in the setting of chronic hemodialysis [ 11 , 12 ], monoclonal gammopathy [ 13 , 14 ], and the administration of trabectedin and pegfilgrastim in the context of liposarcoma in 1 case [ 15 ]. Cardiovascular risk factors, atherosclerotic vascular disease, and monoclonal gammopathy have also been described in association with DDAB.…”

Diffuse Dermal Angiomatosis: A Clue to the Diagnosis of Atherosclerotic Vascular Disease

“…In addition, all reported patients had multiple atherosclerotic comorbidities such as hypertension, dyslipidemia, diabetes mellitus, chronic kidney disease and heavy smoking. Most of them had undergone revascularization procedures, and all lesions rapidly healed shortly after the procedures [ 2 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. However, one reported patient who received conservative medical therapy, which included oral prednisolone and colchicine, died from severe sepsis.…”