Differentiation of CT scan diagnosis between minimal fat renal angiomyolipoma with sufficient blood supply and clear cell renal carcinoma

Guo, Yan; Qian, Peng; Wang, Zhuo; Liu, Mingjuan; Yuan, Xufeng; Long, Teng

doi:10.1007/s10330-011-0731-9

Cited by 2 publications

(2 citation statements)

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“…It is difficult to differentiate them merely through CT [45]. Kimet al [6] compared various CT features of AML with minimal fat with those of size-matched RCCs and found that biphasic helical imaging may be useful in differentiating AML with minimal fat from RCC, with homogeneous tumor enhancement and prolonged enhancement pattern being the most valuable CT findings.…”

Section: Discussionmentioning

confidence: 99%

“…Similar to clear cell renal carcinoma, AML with minimal fat also appears to exhibit abnormal enhancement with a “fast-in-and-fast-out” pattern during the early phase that is easily misdiagnosed as renal cancer. It is difficult to differentiate them merely through CT [45] . Kimet al [6] compared various CT features of AML with minimal fat with those of size-matched RCCs and found that biphasic helical imaging may be useful in differentiating AML with minimal fat from RCC, with homogeneous tumor enhancement and prolonged enhancement pattern being the most valuable CT findings.…”

Section: Discussionmentioning

confidence: 99%

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Study of 320-Slice Dynamic Volume CT Perfusion in Different Pathologic Types of Kidney Tumor: Preliminary Results

et al. 2014

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ObjectiveTo investigate microcirculatory differences between pathologic types of kidney tumor using 320-slice dynamic volume CT perfusion.MethodsPerfusion imaging with 320-slice dynamic volume CT was prospectively performed in 85 patients with pathologically proven clear cell renal cell carcinoma (RCC) (n = 66), papillary RCC (n = 7), chromophobe RCC (n = 5), angiomyolipoma (AML) with minimal fat (n = 7), or RCC (n = 78). Equivalent blood volume (Equiv BV), permeability surface-area product (PS; clearance/unit volume = permeability), and blood flow (BF) of tumor and normal renal cortex were measured and analyzed. Effective radiation dose was calculated.ResultsThere was a significant difference in all three parameters between tumor and normal renal cortex (P<0.001). Equiv BV was significantly different between RCC and AML with minimal fat (P = 0.038) and between clear cell RCC and AML with minimal fat (P<0.001). Mean Equiv BV and BF were significantly higher in clear cell RCC than in papillary RCC (P<0.001 for both) and mean Equiv BV was higher in clear cell RCC than in chromophobe RCC (P<0.001). The effective radiation dose of the CT perfusion protocol was 18.5 mSv.ConclusionPerfusion imaging using 320-slice dynamic volume CT can be used to evaluate hemodynamic features of the whole kidney and kidney tumors, which may be useful in the differential diagnosis of these four pathologic types of kidney tumor.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%