Differentiation grade for extrahepatic bile duct adenocarcinoma: Assessed by diffusion-weighted imaging at 3.0-T MR

Huang, Xinqiao; Shu, Jiwu; Luo, Li; Jin, Ming-Li; Lü, Xiaofei; Yang, Shu-Gen

doi:10.1016/j.ejrad.2016.09.004

Cited by 4 publications

(2 citation statements)

References 21 publications

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“…In our study, the diagnostic accuracy for PSOLs by MRI was 91.17%, which is similar to a previous study [6]. The similarity may be attributed to DCE-MRI, which can quantify the blood flow, microvascular, and capillary permeability of tumors [27]. Meanwhile, DWI can provide information about the biological structures and functional locations at the cellular and molecular levels, which is superior to that offered by conventional MRI [28].…”

Section: Discussionsupporting

confidence: 86%

Combination of CEUS and MRI for the diagnosis of periampullary space-occupying lesions: a retrospective analysis

et al. 2019

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Background The value of magnetic resonance imaging (MRI), contrast-enhanced ultrasound (CEUS), and the combination of CEUS and MRI (CCWM) for the diagnosis of periampullary space-occupying lesions (PSOL) was investigated. Methods A total of 102 patients diagnosed with PSOLs by surgery or biopsy were recruited retrospectively. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI, CEUS, and CCWM were analyzed. Results MRI, CEUS, and CCWM allowed for the accurate detection of 91.17, 92.15, and 99.01% of PSOLs, respectively. The specificity, PPV, and accuracy of CCWM were significantly different from MRI and CEUS ( p < 0.05). However, there the sensitivity and NPV were not significantly different among the three diagnostic technologies. In addition, the specificity, PPV, and accuracy were not significantly different between MRI and CEUS (all p > 0.05). Conclusions CCWM is valuable for differentiating benign and malignant PSOL, which provides important guiding significances for the clinic.

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Section: Discussionsupporting

confidence: 86%

Combination of CEUS and MRI for the diagnosis of periampullary space-occupying lesions: a retrospective analysis

et al. 2019

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“…Earlier studies have reported the primary tumor's superficial spread or extension in 31.6-39.3% of BTC cases, with more than 20-mm length of superficial spread in 14.6-17.9% cases [6,7]. These lesions can be identified using ultrasonography [8], multi detector-row computed tomography (MDCT) [9], and magnetic resonance imaging [10]. Intraductal ultrasonography (IDUS) during endoscopic retrograde cholangiopancreatography (ERCP) has been shown to be beneficial for both qualitative diagnosis and the diagnosis of the main tumor's superficial spread [11,12].…”

Section: Introductionmentioning

confidence: 99%

Form-Vessel Classification of Cholangioscopy Findings to Diagnose Biliary Tract Carcinoma’s Superficial Spread

Fukasawa

Takano

Fukasawa

et al. 2020

IJMS

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We aimed to evaluate a newly developed peroral cholangioscopy (POCS) classification system by comparing classified lesions with histological and genetic findings. We analyzed 30 biopsied specimens from 11 patients with biliary tract cancer (BTC) who underwent POCS. An original classification of POCS findings was made based on the biliary surface’s form (F factor, 4 grades) and vessel structure (V-factor, 3 grades). Findings were then compared with those of corresponding biopsy specimens analyzed histologically and by next-generation sequencing to identify somatic mutations. In addition, the histology of postoperative surgical stumps and preoperative POCS findings were compared. Histological malignancy rate in biopsied specimens increased with increasing F- and V-factor scores (F1, 0%; F1, 25%; F3, 50%; F4, 62.5%; p = 0.0015; V1, 0%; V2, 20%; V3, 70%; p < 0.001). Furthermore, we observed a statistically significant increase of the mutant allele frequency of mutated genes with increasing F- and V-factor scores (F factor, p = 0.0050; V-factor, p < 0.001). All surgical stumps were accurately diagnosed using POCS findings. The F–V classification of POCS findings is both histologically and genetically valid and will contribute to the methods of diagnosing the superficial spread of BTC tumors.

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Factors influencing apparent diffusion coefficient value in extrahepatic cholangiocarcinoma: A retrospective study

Yang

Quan

Huang

et al. 2022

European Journal of Radiology

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Differentiation grade for extrahepatic bile duct adenocarcinoma: Assessed by diffusion-weighted imaging at 3.0-T MR

Cited by 4 publications

References 21 publications

Combination of CEUS and MRI for the diagnosis of periampullary space-occupying lesions: a retrospective analysis

Combination of CEUS and MRI for the diagnosis of periampullary space-occupying lesions: a retrospective analysis

Form-Vessel Classification of Cholangioscopy Findings to Diagnose Biliary Tract Carcinoma’s Superficial Spread

Factors influencing apparent diffusion coefficient value in extrahepatic cholangiocarcinoma: A retrospective study

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