2019
DOI: 10.1101/703249
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Differential pulmonary immunopathologic response of domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) to Mycoplasma ovipneumoniae infection: a retrospective study

Abstract: Mycoplasma ovipneumoniae is a respiratory pathogen that can impact domestic sheep (Ovis aries; DS) and bighorn sheep (Ovis canadensis; BHS). Experimental and field data have indicated BHS are more susceptible than DS to developing polymicrobial pneumonia associated with Mycoplasma ovipneumoniae infection. We hypothesized that DS and BHS have a differential immunopathologic pulmonary response to M. ovipneumoniae infection. A retrospective study was performed using formalin-fixed, paraffin-embedded (FFPE) lung t… Show more

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“…There is strong evidence that the immunopathologic response to M. ovipneumoniae differs between domestic and wild sheep (Grossman et al . 2019 ), often resulting in more detrimental effects of the pathogen to wild sheep. Recently, Mousel et al .…”
Section: Persistent and Emerging Issuesmentioning
confidence: 99%
See 1 more Smart Citation
“…There is strong evidence that the immunopathologic response to M. ovipneumoniae differs between domestic and wild sheep (Grossman et al . 2019 ), often resulting in more detrimental effects of the pathogen to wild sheep. Recently, Mousel et al .…”
Section: Persistent and Emerging Issuesmentioning
confidence: 99%
“…A perceived concern about disease transmission between domestic and wild (Ovis canadensis) sheep has been raised (Onderka & Wishart 1988;Lawrence et al 2010; (Hendrickson 2015). There is strong evidence that the immunopathologic response to M. ovipneumoniae differs between domestic and wild sheep (Grossman et al 2019), often resulting in more detrimental effects of the pathogen to wild sheep. Recently, Mousel et al (2021) has presented research that could aid in solving the problem of disease transmission between wild and domestic sheep.…”
Section: Persistent and Emerging Issuesmentioning
confidence: 99%