Differences and overlap in self-reported symptoms of bipolar disorder and borderline personality disorder

Baryshnikov, Ilya; Aaltonen, Kari; Koivisto, Maaria; Näätänen, Petri; Karpov, Boris; Melartin, Tarja; Heikkinen, Martti; Ketokivi, Mikko; Joffe, Grigori; Isometsä, Erkki

doi:10.1016/j.eurpsy.2015.08.002

Cited by 17 publications

(17 citation statements)

References 38 publications

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“…Conversely, in bipolar disorder, childhood trauma is associated with more severe clinical presentation, such as psychotic features (Aas et al, 2016), supporting the connection between mania, psychosis, and trauma. Many patients reported manic symptoms in the current sample, but it is notable that, used dimensionally, MDQ does not assess bipolar disorder specifically, but overlaps with borderline personality features (Baryshnikov et al, 2015;Zimmerman et al, 2010). The emergence of borderline personality has been associated with early life adversity in previous literature (Brüne, 2016;Newnham and Janca, 2014).…”

Section: Adversities and Symptomatologymentioning

confidence: 76%

“…Mood Disorders Questionnaire, MDQ (Hirschfeld, 2002), assesses lifetime manic symptoms. To assess manic symptoms dimensionally, MDQ was used as a sum score of 13 part A symptom items answered as yes/no, which is a commonly used measure in research (Baryshnikov et al, 2015). Sense of Mastery was used to measure positive mental health (sense of having control over the forces that affect one's life) (Pearlin et al, 1981).…”

Section: Questionnairementioning

confidence: 99%

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Childhood adversities and clinical symptomatology in first-episode psychosis

Lindgren

Mäntylä

Rikandi

et al. 2017

Psychiatry Research

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In addition to severe traumatic experiences, milder, more common childhood adversities reflecting psychosocial burden may also be common in people with psychotic disorders and have an effect on symptomatology and functioning. We explored eleven negative childhood experiences and their influence on clinical symptoms among young adults with first-episode psychosis (FEP, n = 75) and matched population controls (n = 51). Individuals with FEP reported more adversities than controls. Specifically serious conflicts within the family, bullying at school, maternal mental health problems, and one's own and parents' serious illness during childhood were experienced by the patients more often than by controls. In the FEP group, the severity of adversity was associated with increased anxiety, manic, and obsessive-compulsive symptoms, but not with the severity of positive psychotic symptoms. Adversity produced a more pronounced effect on symptoms in male patients than in female patients. To conclude, in line with earlier studies of more chronic psychosis, a majority of the participants with FEP reported exposure to childhood adversities, with the FEP group reporting more adversities than controls. High levels of mood and anxiety symptoms in patients with FEP may be related to cumulative exposure to childhood adversities. This should be taken into account in the treatment for FEP.

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Section: Adversities and Symptomatologymentioning

confidence: 76%

Section: Questionnairementioning

confidence: 99%

Childhood adversities and clinical symptomatology in first-episode psychosis

Lindgren

Mäntylä

Rikandi

et al. 2017

Psychiatry Research

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“…The origins of self-reported features of BPD, as well as their risk factors in patients seeking treatment for mood disorders are incompletely understood. Our previous study indicated that self-reported features mood instability and impulsivity are shared between BPD and bipolar disorders (Baryshnikov et al, 2015). Overall, mood instability among mood disorder patients may be also related to inherited vulnerability to emotional dysregulation (Koenigsberg, 2010;Peng et al, 2015;Stein et al, 2009).…”

Section: Introductionmentioning

confidence: 93%

“…BPD is often comorbid with mood disorders (Links and Eynan, 2013;Mantere et al, 2006;McGlashan et al, 2000;Melartin et al, 2002a;Riihimaki et al, 2014) and according to self-report, symptoms of BPD are abundantly present in patients with mood disorders (Baryshnikov et al, 2015(Baryshnikov et al, , 2016a. However, the validity of personality assessment in patients with mood disorders is debatable (Morey et al, 2010;Zimmerman, 1994).…”

Section: Introductionmentioning

confidence: 99%

Relationships between self-reported childhood traumatic experiences, attachment style, neuroticism and features of borderline personality disorders in patients with mood disorders

Baryshnikov

Joffe

Koivisto

et al. 2017

Journal of Affective Disorders

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We found moderately strong correlations between self-reported BPD features and concurrent high neuroticism, reported childhood traumatic experiences and Attachment Anxiety also among patients with mood disorders. Independent predictors for BPD features include young age, frequency of childhood traumatic experiences and high neuroticism. Insecure attachment may partially mediate the relationship between childhood traumatic experiences and borderline features among mood disorder patients.

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“…Dabei ist natürlich dann auch die Differenzialdiagnose einer Borderline-Persönlichkeitsstörung zu beachten, die ebenfalls als Kernmerkmal eine emotionale Instabilität aufweist. Diese differenzialdiagnostischen Überlegungen sind zum Teil durchaus komplex: Insbesondere besteht die Gefahr, eine Borderline-Persönlichkeitsstörung fälschlicherweise als hochfrequentes Rapid Cycling zu diagnostizieren [40]. Dies hat natürlich eine hohe therapeutische Bedeutung (Fokus auf Pharmakotherapie vs. Psychotherapie), weshalb eine achtsame Differenzialdiagnostik an dieser Stelle notwendig ist [41], unter Berücksichtigung einer ebenfalls hohen Komorbiditätsrate bipolarer Störungen mit Persönlichkeitsstörungen [42].…”

Section: äTiologieunclassified

Rapid Cycling bei bipolar-affektiven Störungen: Klinik, Ätiologie und Behandlungsempfehlungen

Köhler¹,

Friedel²,

Stamm³

2017

Fortschr Neurol Psychiatr

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Rapid cycling bipolar disorder is encountered frequently in clinical practice with a lifetime prevalence of up to 31 %. Besides its association with greater illness severity, increased suicide and comorbidity rates, rapid cycling bipolar disorder has been closely associated with a longer and more complicated course of disease and inadequate treatment response compared to non-rapid cycling bipolar disorder. However rapid cycling does not serve as a stable characteristic of bipolar disorder, though its prevalence increases with illness duration. Female gender, hypothyreoidism and antidepressant medications have been suggested as correlates of rapid cycling bipolar disorder; however, the interaction amongst these factors make an interpretation of their causal relations difficult. Only very few data are available from randomized clinical trials that investigated the therapeutic options of rapid cycling bipolar disorder. Based on these trials, the therapeutic outcome of lithium is similar to that of the class of anticonvulsants. Positive treatment outcome reported for atypical neuroleptics is often based on pharmaceutical company-financed, placebo-controlled RCTS. Altogether independent prospective RCTs and head-to-head comparisons are lacking that can provide sufficient information on treatment response. In addition, the role of antidepressant treatment in the course and phase acceleration of bipolar disorder remains insufficiently understood. However, in the light of present empirical evidence, the use of antidepressant medication in the treatment of rapid cycling bipolar disorder has to be looked at highly critically.

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Differences and overlap in self-reported symptoms of bipolar disorder and borderline personality disorder

Abstract: The MDQ and MSI items of "affective instability", "impulsivity", "irritability", "flight of thoughts" and "distractibility" appear to overlap in content. The other scale items are more disorder-specific, and thus, may help to distinguish BD and BPD.

Cited by 17 publications

References 38 publications

Childhood adversities and clinical symptomatology in first-episode psychosis

Childhood adversities and clinical symptomatology in first-episode psychosis

Relationships between self-reported childhood traumatic experiences, attachment style, neuroticism and features of borderline personality disorders in patients with mood disorders

Rapid Cycling bei bipolar-affektiven Störungen: Klinik, Ätiologie und Behandlungsempfehlungen

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