Dietary supplements for chronic gout

Andrés, Mariano; Sivera, Francisca; Falzon, Louise; Buchbinder, Rachelle; Carmona, Loreto

doi:10.1002/14651858.cd010156.pub2

Cited by 23 publications

(17 citation statements)

References 40 publications

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“…Andrés M. et al, reviewed 2 randomized controlled trial for vitamin C and enriched skim milk powder supplement and reported that routine dietary supplementation for Gout patients cannot be recommended because of paucity of high-quality evidence [9]. In 2012, American College of Rheumatology has published a guideline for management of Gout but screening or treatment for vitamin B12 was not discussed [6].…”

Section: Discussionmentioning

confidence: 99%

Cyanocobalamin and 25-Hydroxy Vitamin D Levels in Gout Patients: An Overlooked Issue

Yandı¹,

Gencer²,

Kılavuz³

et al. 2016

OJRA

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Gout is one of the most frequent type of inflammatory arthritis in developed countries. The elevation of serum uric acid levels and the deposition of monosodium urate crystals in joints and/or soft tissues are the mechanisms of pathogenesis. Uric acid is a product of the metabolic cleavage of purine nucleotides and organ meats, beef, pork, and lamb, anchovies, sardines, herring, mackerel, scallops, gravy and beer are known to be very rich in purine. On the other hand, some of these foods are also the main sources of vitamin B12 (cyanocobalamin). As a chronic inflammatory arthritis corticosteroids are frequently prescribed for gout patients, meaning a higher risk for osteoporosis which may be blocked by daily calcium and vitamin D replacement. However, there are no recommendations about screening or replacement of Gout patients for vitamin D and B12. Herein, we evaluated our patients retrospectively to document their vitamin levels and also to find the factors associated with vitamin deficiency. Totally, 90 patients, 71 (79.9%) male and 19 (20.1%) female patients with a median diagnostic age of 55 (19-80) were included. Thirty six (40%) patients were newly diagnosed (group 1) but 54 (60%) patients had established diseases (group-2) with median disease duration of 36 (11-240) months. Nearly half (47.2%) of the patients in group-1 and 37% of the patients in group-2 had vitamin B 12 deficiency. Similarly, 38.9% in each group had vitamin D deficiency and 52.8% in group-1 and 44.4% in group-2 had vitamin D insufficiency. In conclusion, we strongly recommend routine screening and replacement of vitamin B12 and D for patients with Gout.

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Section: Discussionmentioning

confidence: 99%

Cyanocobalamin and 25-Hydroxy Vitamin D Levels in Gout Patients: An Overlooked Issue

Yandı¹,

Gencer²,

Kılavuz³

et al. 2016

OJRA

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“…Contrary to a study conducted in the USA 16 but in agreement with another conducted in Scandinavia 26 , the prevalence of DS users decreased. Possible explanations include the absence or low efficiency of DS [27][28][29][30] and tighter regulations regarding their health claims 31 . Still, it would be of interest that the decrease observed in this study could be confirmed by other independent studies.…”

Section: Trends and Determinants Of Dietary Supplements Usementioning

confidence: 99%

Trends in vitamin, mineral and dietary supplement use in Switzerland. The CoLaus study

Marques‐Vidal¹,

Vollenweider²,

Waeber³

2016

Eur J Clin Nutr

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Background: vitamin/mineral (VMS) and dietary supplements (DS) use is common in Switzerland, but nothing is known regarding the factors associated with their initiation, discontinuation or continuation of intake. Methods: prospective study conducted between 2003-6 and 2009-12 in Lausanne, Switzerland among 4676 participants (2525 women, age range 35-75 years). VMS were defined as single or multivitamin/multimineral preparations; DS were defined as any dietary supplement. Results: VMS use was 20.6% at baseline and 20.3% at follow-up (p=0.69): 559 (12.0%) participants discontinued; 545 (11.7%) initiated and 404 (8.6%) continued VMS use. On multivariable analysis, men had a lower relative risk ratio (RRR) of discontinuing, initiation or continuing; older age and being physically active were associated with a higher RRR of initiation or continuing; lower education and higher body mass index were associated with a lower RRR of discontinuing or continuing of VMS. DS use decreased from 10.4% to 6.8% (p<0.001): 405 (8.7%) participants discontinued; 239 (5.1%) initiated and 81 (1.7%) continued DS use. On multivariable analysis, men had a lower RRR of discontinuing, initiation or continuing; older age had a higher RRR of initiation, discontinuing or continuing; being physically active was associated with a higher RRR of initiation or continuing; Swiss citizens and former smokers had a higher RRR of discontinuing. Conclusion: VMS use is stable in the Lausanne population, while DS use appears to be decreasing. Individuals can be categorized either as users or non-users depending on the study period, and consistent users are only a small fraction of prevalent users.

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“…Many studies based on the Third National Health and Nutrition Examination Survey (NHANES‐III) suggest that dietary consumption affects SUA levels which is parallel to the increase in the risk of gout . The relationship between diet, drinking and gout was found a long time ago . In this review, we will update the recent data of the association between vitamin C (VC), alcohol, tea, coffee, milk and yogurt with SUA and gout risk as shown in Table .…”

Section: Introductionmentioning

confidence: 99%

The association of vitamin C, alcohol, coffee, tea, milk and yogurt with uric acid and gout

Towiwat

2015

Int J of Rheum Dis

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About 2500 years ago, gout was observed by Hippocrates and many people suffered severe pain and deformity. Lifestyle and diet play a significant role in gout and serum uric acid levels. Epidemiological and research studies have supported this evidence. Many recommendations and guidelines from different parts of the world mention the impact of diet on gout. Recently, new research has shown associations between vitamin C, alcohol, coffee, tea, milk and yogurt with uric acid and the risk of gout. Our review summarizes recently published research regarding dietary impact on the risk of gout and serum uric acid levels.

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Dietary supplements for chronic gout

Cited by 23 publications

References 40 publications

Cyanocobalamin and 25-Hydroxy Vitamin D Levels in Gout Patients: An Overlooked Issue

Cyanocobalamin and 25-Hydroxy Vitamin D Levels in Gout Patients: An Overlooked Issue

Trends in vitamin, mineral and dietary supplement use in Switzerland. The CoLaus study

The association of vitamin C, alcohol, coffee, tea, milk and yogurt with uric acid and gout

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