2019
DOI: 10.3390/nu11122977
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Abstract: Survivors of childhood acute lymphoblastic leukemia (cALL) are at high risk of developing dyslipidemia, including low HDL-cholesterol (HDL-C). This study aimed to examine the associations between food/nutrient intake and the levels of HDL-C in a cohort of children and young adult survivors of cALL. Eligible participants (n = 241) were survivors of cALL (49.4% boys; median age: 21.7 years old) recruited as part of the PETALE study. Nutritional data were collected using a validated food frequency questionnaire. … Show more

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Cited by 11 publications
(11 citation statements)
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“…Previous study has supported the view that cancers might affect cholesterol metabolism or utilization due to plasma cholesterol levels reverted to normal after cancer remission (Yun et al, 2019). Second, it is worth considering other confounding factors, such as variety of food intake and dyslipidemia, because these factors could also increase the risk of cancer (Morel et al, 2019). In addition, the candidates selected for the clinical samples in the present study were all Chinese.…”
Section: Disscusionsupporting
confidence: 57%
“…Previous study has supported the view that cancers might affect cholesterol metabolism or utilization due to plasma cholesterol levels reverted to normal after cancer remission (Yun et al, 2019). Second, it is worth considering other confounding factors, such as variety of food intake and dyslipidemia, because these factors could also increase the risk of cancer (Morel et al, 2019). In addition, the candidates selected for the clinical samples in the present study were all Chinese.…”
Section: Disscusionsupporting
confidence: 57%
“…In our study, a better adherence to the MEDAS score was inversely associated with the risk of having low HDL-C, whereas positive associations were found with a more pro-inflammatory diet (E-DII score) and higher intake of ultra-processed foods. Previously, our group has highlighted the influence of nutrient and food group intakes on the risk of having low HDL-C in the PETALE cohort [ 39 ]. In Brazilian adults without cancer, a Traditional dietary pattern, characterized by a high consumption of rice and legumes and a low consumption of red meat, fat and sugar was associated with higher HDL-C [ 27 ].…”
Section: Discussionmentioning
confidence: 99%
“…Fasting insulin (pmol/L), glucose (mmol/L), total cholesterol (TC, mmol/L), triglycerides (mmol/L), low-density lipoprotein-cholesterol (LDL-C, mmol/L), high-density lipoprotein-cholesterol (HDL-C, mmol/L), apolipoproteins A-1 (Apo A-1, mg/mL) and B-100 (Apo B-100, g/L) and low-grade and visceral inflammation [C-reactive protein (CRP, μg/mL), tumor necrosis factor (TNF, pg/mL)-α, interleukin (IL, pg/mL)-6, adiponectin (ng/mL) and leptin (ng/mL)] were measured on fasting blood, as described previously [ 9 , 38 ]. The homeostasis model assessment of insulin resistance (HOMA-IR) was calculated [ 39 ]. Cardiometabolic complications were defined and categorized [ 9 ]—obesity (yes or no), pre-hypertension/hypertension (yes or no), insulin resistance (yes or no) and dyslipidemia (yes or no).…”
Section: Methodsmentioning
confidence: 99%
“…HDL-C is an important lipoprotein that plays a protective role in cardiovascular diseases and previous studies showed that diet can influence serum levels of HDL-C significantly. 36,37 The intake of specific nutrients such as proteins, folate and magnesium has been associated with higher blood levels of HDL-C. 38 Previously, a cross-sectional study of children aged 3-17 years old in Greece also highlighted the influence of a poor diet quality, assessed by HEI, on the risk of having low HDL-C. 39 Compared to Western populations, Asian populations tend to have a greater percentage of obesity even with normal BMI. Moreover, obesity is associated with not only MetS but also high BP, high TG, and high FG.…”
Section: Food and Function Papermentioning
confidence: 99%