Dietary flavonoids from Allium mongolicum Regel promotes growth, improves immune, antioxidant status, immune-related signaling molecules and disease resistance in juvenile northern snakehead fish (Channa argus)

Li, Muyang; Zhu, Xin‐Ming; Tian, Jingkui; Ming, Lei; Wang, Guiqin

doi:10.1016/j.aquaculture.2018.12.011

Cited by 130 publications

(69 citation statements)

References 43 publications

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“…The main phenolic acids found in alliums include p-Coumaric acid, ferulic acid, sinapic acid, gallic acid, and protocatechuic acid [38]. However, very few studies used allium flavonoids as feed additives to promote growth, immune, and antioxidant response for animals [39,40].…”

Section: Polyphenolic Compoundsmentioning

confidence: 99%

The Genus Allium as Poultry Feed Additive: A Review

Kothari

Lee

Niu

et al. 2019

Animals

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The genus Allium, belonging to the family Amaryllidaceae has been known since ancient times for their therapeutic potentials. As the number of multi-drug resistant infections has increased due to in-feed antibiotic usage in poultry, the relevance of alliums as feed additives has been critically assessed. Garlic and the other Allium species, such as onions, leek, shallot, scallion, and chives, have been characterized to contain a plethora of bioactive compounds such as organosulfur compounds, polyphenols, saponins, fructans, and fructo-oligosaccharides. Consequently, alliums have been validated to confer antioxidant, antibacterial, antiviral, immunostimulatory, gut homeostasis, and lipid- as well as cholesterol-lowering properties in poultry. This review intends to summarize recent progress on the use of edible alliums as poultry feed additives, their beneficial effects, and the underlying mechanisms of their involvement in poultry nutrition. Perspectives for future research and limitations are also briefly discussed.

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Section: Polyphenolic Compoundsmentioning

confidence: 99%

The Genus Allium as Poultry Feed Additive: A Review

Kothari

Lee

Niu

et al. 2019

Animals

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“…Organisms usually have a sophisticated antioxidant defence system to remove excessive free radicals and protect fine cells from oxygen damage. Antioxidant enzymes generally have SOD, CAT, T‐AOC, ASA and MDA, which play a role mainly by blocking and scavenging free radicals (Feng et al., 2016; Li, Zhu, et al, 2019). In this study, compared with the control, SOD and T‐AOC activities were significantly increased in gill, hepatopancreas, gut, kidney and serum of B12 group, CAT activity was significantly increased in gill, hepatopancreas, gut and kidney, and ASA level was significantly increased in gill and serum, while MDA was attenuated.…”

Section: Discussionmentioning

confidence: 99%

Dietary supplementation of microbial floc heightens growth and improves digestive, immune, antioxidant enzymes activity and ammonia resistance in Opsariichthys kaopingensi s

et al. 2020

Aquac Res

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The present study was conducted to evaluate the effects of dietary supplementation of microbial floc on growth, digestive and immune enzymes activity, antioxidant status and ammonia resistance in Opsariichthys kaopingensis. Four hundred fifty healthy O. kaopingensis juveniles (6.21 ± 0.32 g) were randomly assigned to 15 tanks. Juvenile fish were fed five experimental diets containing microbial floc 0 (B0 control), 4% (B4), 8% (B8), 12% (B12) and 16% (B16), respectively, for 30 days. Results showed that B12 could significantly enhance weight gain rate (WGR), specific growth rate (SGR) and protein efficiency ratio (PER), reduce feed conversion rate (FCR) (p < .05), compared to the control. The activity of protease, lipase and amylase in hepatopancreas and gut of B12 group were higher than that of the control (p < .05). Also, significant increases in lysozyme (LSZ), glutamic pyruvic transaminase (GPT) and alkaline phosphatase (AKP) activities of O. kaopingensis were found at B12 group (p < .05). Comparing the antioxidant capacity, the activities of superoxide dismutase (SOD), total antioxidant capacity (T‐AOC), catalase (CAT) and ascorbic acid (ASA) of juveniles in B12 group were significant highly (p < .05) than control, and the content of malondialdehyde (MDA) was much lower than control in gill, kidney, hepatopancreas, intestine and serum under this experiment condition. After ammonia challenge, survival rate in all dietary supplementation of microbial floc treatment groups was significantly increased (p < .05). Overall, these findings suggest that dietary supplementation of microbial floc enhanced growth, digestion, antioxidant and immune response, and increased ammonia stress resistance in O. kaopingensis. The suitable supplemental level of approximately 12% microbial floc was recommended in the present study.

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“…Cell lysates were collected to detect antioxidant parameters. The levels of CAT, GPx, SOD and MDA were measured according to the methods described in our previous study (Li, Zhu, Tian, et al, 2019).…”

Section: Methodsmentioning

confidence: 99%

“…Due to the large demand in the aquatic product market, C. argus culture is mainly based on high density and intensive aquaculture (Li, Zhu, Tian, Liu, & Wang, 2018). Intensive aquaculture has generated a variety of environmental stressors and increased the susceptibility of this fish to various pathogens (Li, Zhu, Tian, Liu, & Wang, 2019). Therefore, the epidemic of C. argus is frequent (Gou et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Amelioration of LPS‐induced inflammatory response and oxidative stress by astaxanthin in Channa argus lymphocyte via activating glucocorticoid receptor signalling pathways

Gao

et al. 2020

Aquac Res

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The present study was conducted to evaluate the effects of astaxanthin (AST) against lipopolysaccharide (LPS)‐induced lymphocyte viability, ultrastructural lesions, apoptosis, oxidative stress and inflammatory responses in Channa argus. Lymphocytes exposed to more than 10 μg/ml LPS alone for 24 hr showed significantly decreased cell viability, elevated nitric oxide (NO) and malondialdehyde (MDA), lactate dehydrogenase (LDH) contents, and increased nuclear factor κB p65 (NF‐κB p65), myeloid differential protein‐88 (MyD88), tumour necrosis factor‐α (TNF‐α), interleukin‐1β (IL‐1β), interleukin‐8 (IL‐8), caspase‐3, caspase‐8 and caspase‐9 gene expression. LPS at a concentration of 10 μg/ml could induce oxidative stress and inflammatory responses in lymphocytes. The activities of antioxidant enzymes (catalase (CAT), glutathione peroxidase (GPx), superoxide dismutase (SOD)) were significantly decreased after exposure to 10 μg/ml LPS. Besides, AST strikingly antagonized the LPS‐induced negative effects. AST significantly increased the expression of HSP70, HSP90, IκB‐α, and glucocorticoid receptor (GR) and decreased inflammatory responses. Further study showed that AST can activate GR signalling pathway and inhibit p65 phosphorylation. In addition, AST attenuated LPS‐induced apoptosis, mitochondrial swelling, degeneration and vacuolization. Collectively, these findings suggest that AST has protective roles in LPS‐induced cell damage via modulating GR activation in C. argus lymphocytes.

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Dietary flavonoids from Allium mongolicum Regel promotes growth, improves immune, antioxidant status, immune-related signaling molecules and disease resistance in juvenile northern snakehead fish (Channa argus)

Cited by 130 publications

References 43 publications

The Genus Allium as Poultry Feed Additive: A Review

The Genus Allium as Poultry Feed Additive: A Review

Dietary supplementation of microbial floc heightens growth and improves digestive, immune, antioxidant enzymes activity and ammonia resistance in Opsariichthys kaopingensi s

Amelioration of LPS‐induced inflammatory response and oxidative stress by astaxanthin in Channa argus lymphocyte via activating glucocorticoid receptor signalling pathways

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