Dienzyme-assisted salting-out extraction of flavonoids from the seeds of Cuscuta chinensis Lam.

Wei, Yingqin; Sun, Manman; Fang, Haiyan

doi:10.1016/j.indcrop.2018.10.068

Cited by 15 publications

(4 citation statements)

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“…Their antioxidant and antiradical activity were confirmed by their ability to suppress ROS produced by macrophages, the isolates being more effective in comparison to the crude extract [ 97 ]. The flavonoid and phenolic content, along with the antioxidant potential may vary and depends on the method of extraction used [ 98 ]. Leaves extract of piper beetle was prepared using sonication, and had a total flavonoid content of 49.79 ± 1.54 mg QE/gm extract, whereas maceration gave 32.10 ± 0.65 mg QE/gm and Soxhlet extraction gave 40.89 ± 0.87 mg QE/gm ( Table 2 ) [ 99 ].…”

Section: Effects Of Flavonoids On Human Healthmentioning

confidence: 99%

Important Flavonoids and Their Role as a Therapeutic Agent

et al. 2020

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Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.

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Section: Effects Of Flavonoids On Human Healthmentioning

confidence: 99%

Important Flavonoids and Their Role as a Therapeutic Agent

et al. 2020

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“…(Family: Convolvulaceae) is one of the most commonly used herbs in TCM. It contains several pharmaceutically active compounds such as phenolic compounds, polysaccharides, lignans, flavonoids and resin glycosides typical for the family Convolvulaceae ( Donnapee et al, 2014 ; Sun et al, 2014 ; Wei et al, 2019a ). C. chinensis has been reported to display anticancer, anti-apoptosis, antioxidant, anti-inflammatory, immunostimulatory, anti-osteoporotic, and hepatoprotective activities, and is also widely used in the clinical treatment of kidney yang-deficiency ( Yang et al, 2011 ; Kang et al, 2014 ; Sun et al, 2014 ; Yang et al, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

Enhanced Healthspan in Caenorhabditis elegans Treated With Extracts From the Traditional Chinese Medicine Plants Cuscuta chinensis Lam. and Eucommia ulmoides Oliv.

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Schmitz‐Linneweber

et al. 2021

Front. Pharmacol.

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To uncover potential anti-aging capacities of Traditional Chinese Medicine (TCM), the nematode Caenorhabditis elegans was used to investigate the effects of Eucommia ulmoides and Cuscuta chinensis extracts, selected by screening seven TCM extracts, on different healthspan parameters. Nematodes exposed to E. ulmoides and C. chinensis extracts, starting at the young adult stage, exhibited prolonged lifespan and increased survival after heat stress as well as upon exposure to the pathogenic bacterium Photorhabdus luminescens, whereby the survival benefits were monitored after stress initiation at different adult stages. However, only C. chinensis had the ability to enhance physical fitness: the swimming behavior and the pharyngeal pumping rate of C. elegans were improved at day 7 and especially at day 12 of adulthood. Finally, monitoring the red fluorescence of aged worms revealed that only C. chinensis extracts caused suppression of intestinal autofluorescence, a known marker of aging. The results underline the different modes of action of the tested plants extracts. E. ulmoides improved specifically the physiological fitness by increasing the survival probability of C. elegans after stress, while C. chinensis seems to be an overall healthspan enhancer, reflected in the suppressed autofluorescence, with beneficial effects on physical as well as physiological fitness. The C. chinensis effects may be hormetic: this is supported by increased gene expression of hsp-16.1 and by trend, also of hsp-12.6.

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“…A new green and sustainable extraction technique, namely osmosis extraction (OE), was first developed based on salting-out extraction (SOE). SOE has attracted much attention recently because it is easy to scale up, inexpensive, and is a green technique [1,2]. The extraction of target products from complex material was based on their selective distribution between the aqueous two-phase system.…”

Section: Introductionmentioning

confidence: 99%

A Novel Green Extraction Technique for Extracting Flavonoids from Folium nelumbinis by Changing Osmosis Pressure

et al. 2020

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A new green and sustainable extraction technique, namely osmosis extraction (OE), was developed for efficient extracting flavonoids from Folium nelumbinis by changing the osmotic pressure. The antioxidant activities of the extracted flavonoids were also evaluated. Ethanol and ammonium sulfate were selected for the OE system because they are environmentally friendly. The maximum flavonoids concentration in the top phase was obtained with an ethanol volume fraction of 42.0% and the salt mass of 1.9 g. The kinetic behavior of the extraction process showed that OE had higher efficiencies especially coupled with ultrasonication due to the accompanying and serious morphological changes of Folium nelumbinis cells observed by digital microscope and nano-computed tomography (nano-CT). Results of morphological and anatomical features showed that the higher intracellular chemical potential made the cell expand and even led to bursting. The results also showed that the extraction efficiency of flavonoids with high antioxidant activities was higher than that of the traditional method. The interface effect enhanced the extraction during the salting-out extraction and osmosis was the main factor that improved the extraction efficiency.

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Dienzyme-assisted salting-out extraction of flavonoids from the seeds of Cuscuta chinensis Lam.

Cited by 15 publications

References 14 publications

Important Flavonoids and Their Role as a Therapeutic Agent

Important Flavonoids and Their Role as a Therapeutic Agent

Enhanced Healthspan in Caenorhabditis elegans Treated With Extracts From the Traditional Chinese Medicine Plants Cuscuta chinensis Lam. and Eucommia ulmoides Oliv.

A Novel Green Extraction Technique for Extracting Flavonoids from Folium nelumbinis by Changing Osmosis Pressure

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