“…High-order cycloaddition reaction represents an extraordinary tool for synthesizing a large number of important medium-sized polycyclic scaffolds in a fairly straightforward manner . In this scene, the tropone and its derivatives have proven to be versatile 4π, 6π, or 8π synthons in processing [4+2], [4+6], [6+3], [6+4], [6+6], [8+2], and [8+3] high-order cycloadditions to build various bridged- or fused-cyclic skeletons, which are highly privileged backbones in the synthesis of bioactive molecules and natural products . In particular, numerous studies have revealed that the use of tropones as a 8π component in cycloaddition with suitable partners can result in efficient access to bicyclic frameworks.…”