Diagnostic yield of routine duodenal biopsies in iron deficiency anaemia: a study from Western Anatolia

Gönen, Can; Yılmaz, Nusret; Yalcin, Muhittin; Şımşek, İlkay; Gönen, Ömür

doi:10.1097/01.meg.0000250583.07867.b7

Cited by 22 publications

(24 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It consists of a large spectrum from overt malabsorption or usual gastrointestinal symptoms to clinically silent conditions (22) . IDA may be found in CD patients even in the lack of diarrhea or steatorrhea.…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Celiac Disease in Patients With Iron-Deficiency Anemia in Center and South Area of Iran

Baghbanian

Farahat

Vahedian

et al. 2015

Arq. Gastroenterol.

View full text Add to dashboard Cite

-Background -Celiac disease is an immune-mediated enteropathy due to a permanent sensitivity to gluten in genetically susceptible people. Iron-deficiency anemia is the most widely experienced anemia in humans. Iron-deficiency anemia additionally is a common extra intestinal manifestation of celiac disease. Objective -To investigate correlation between tTg levels and histological alterations and then to determine the prevalence of celiac disease in Center and South area patients of Iran with iron deficiency anemia. Methods -A total of 402 patients aged 12-78 years who presented with iron-deficiency anemia were included in this study. Hemoglobin, mean corpuscular volume and serum ferritin were determined. Venous blood samples for anti-tissue transglutaminase antibody immunoglobuline A and G were obtained from these patients. Upper gastrointestinal endoscopy was recommended to patients who had positive serology.

show abstract

Section: Discussionmentioning

confidence: 99%

The Prevalence of Celiac Disease in Patients With Iron-Deficiency Anemia in Center and South Area of Iran

Baghbanian

Farahat

Vahedian

et al. 2015

Arq. Gastroenterol.

View full text Add to dashboard Cite

show abstract

“…Total (n) 14 15 29 silent cases [3]. IDA is a common extraintestinal manifestation of CD and has been described as the sole manifestation of the disease [4,5].…”

Section: Severe Lesions Minimal Lesions Total (N)mentioning

confidence: 99%

Diagnostic Yield of Routine Duodenal Biopsies in Iron Deficiency Anemia for Celiac Disease Diagnosis

et al. 2013

View full text Add to dashboard Cite

Background. Iron deficiency anemia (IDA) is a recognised feature of celiac disease (CD) in adults and can be its only presentation. Aim. To define the prevalence of CD in Moroccan adult patients with IDA of obscure origin and to determine the yield of small bowel biopsy performed during routine endoscopy. Methods. 437 patients with IDA of obscure origin were included. 4 endoscopic mucosal biopsies were taken from the second part of duodenum and 2 biopsies from antrum and fundus, respectively. Endoscopic aspect and severity of anemia were correlated with histological diagnoses using coefficient Kappa. Results. 29 out of 437 patients (6.63%) had CD. Endoscopic aspect was normal in 66%, a mosaic pattern of mucosa in 17%, and scalloping of the small bowel folds in 17%. 12 patients had Marsh III, 8 had Marsh II, 6 had Marsh I, and 3 had Marsh IV lesions. There was no correlation between degree of anemia, endoscopic aspect, and severity of duodenal lesions (Kappa = −0.167). Conclusion. Routine duodenal biopsy gives an additional 6.63% diagnostic benefit of CD and should be indicated in all patients with IDA. The finding of normal endoscopic appearance of mucosa should not preclude duodenal biopsies.

show abstract

“…Entre estos destacan los siguientes: metronidazol, tinidazol y furazolidona (que son nitroimidazoles), albendazol (un bencimidazol) y quinacrina (una acridina sustituta). También se ha demostrado la utilidad de la paromicina en algunas situaciones y se ha propuesto la nitazoxanida como alternativa a los nitroimidazoles convencionales; sin embargo, es imprescindible la realización de más estudios para evaluar por completo su eficacia [1,14,44,45] . No obstante, en el momento actual, los nitroimidazoles (metronidazol y tinidazol) y el albendazol son los fármacos de elección para el tratamiento de las infecciones por Giardia [1] .…”

Section: Tratamiento Y Controlunclassified

Giardiasis: Conceptos modernos sobre su control y tratamiento

Thompson¹

2008

Ann Nestlé [Esp]

View full text Add to dashboard Cite

Giardia es el patógeno protozoario entérico más corriente en humanos, animales domésticos y animales salvajes. El riesgo máximo de las consecuencias clínicas de la infección por Giardia recae en los niños, particularmente los que habitan en países en vías de desarrollo, en asentamientos comunitarios en condiciones desventajosas. Los estudios de epidemiología molecular han contribuido a aclarar las fuentes de infección y la significación de los reservorios animales para la salud pública. Aunque en la actualidad se conocen aspectos de la patogénesis de la infección por Giardia, estamos todavía muy lejos de poder comprender los factores que predisponen a la enfermedad clínica. Existe la disponibilidad de fármacos eficaces para tratar las infecciones por Giardia, pero sólo pueden actuar como coadyuvantes de los abordajes de salud pública tradicionales en los entornos endémicos donde los niños están frecuentemente infectados.

show abstract

Diagnostic yield of routine duodenal biopsies in iron deficiency anaemia: a study from Western Anatolia

Cited by 22 publications

References 21 publications

The Prevalence of Celiac Disease in Patients With Iron-Deficiency Anemia in Center and South Area of Iran

The Prevalence of Celiac Disease in Patients With Iron-Deficiency Anemia in Center and South Area of Iran

Diagnostic Yield of Routine Duodenal Biopsies in Iron Deficiency Anemia for Celiac Disease Diagnosis

Giardiasis: Conceptos modernos sobre su control y tratamiento

Contact Info

Product

Resources

About