2019
DOI: 10.1155/2019/4360612
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Abstract: A growing interest in the usability of saliva has been observed recently. Using saliva as a diagnostic material is possible because it contains a varied range of composites, organic and inorganic like proteins, carbohydrates, and lipids, which are secreted into saliva. Moreover, this applies to drugs and their metabolites. Saliva collection is noninvasive, and self-collection is possible. There is a lack of risk of injuries related to injection with needle, and it is generally safe. Human saliva has been succe… Show more

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Cited by 32 publications
(41 citation statements)
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References 55 publications
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“…It is also worth noting that the composition of saliva reflects dynamic changes in the body, which makes this fluid an excellent tool for determining clinically useful biomarkers [12][13][14][15]. Salivary redox biomarkers are used in the diagnosis of diseases of affluence (obesity, insulin resistance, diabetes, chronic kidney disease) [16][17][18], neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, dementia) [19,20], or cancer (colorectal, breast, ovarian cancer) [21,22]. However, salivary redox homeostasis has not been evaluated yet in patients with chronic heart failure.…”
Section: Introductionmentioning
confidence: 99%
“…It is also worth noting that the composition of saliva reflects dynamic changes in the body, which makes this fluid an excellent tool for determining clinically useful biomarkers [12][13][14][15]. Salivary redox biomarkers are used in the diagnosis of diseases of affluence (obesity, insulin resistance, diabetes, chronic kidney disease) [16][17][18], neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, dementia) [19,20], or cancer (colorectal, breast, ovarian cancer) [21,22]. However, salivary redox homeostasis has not been evaluated yet in patients with chronic heart failure.…”
Section: Introductionmentioning
confidence: 99%
“…Saliva is becoming an increasingly popular body fluid in laboratory medicine [12][13][14][15]. It is a non-invasive diagnostic tool, the collection of which is particularly convenient for children and teenagers [13,14].…”
Section: Introductionmentioning
confidence: 99%
“…Saliva is becoming an increasingly popular body fluid in laboratory medicine [12][13][14][15]. It is a non-invasive diagnostic tool, the collection of which is particularly convenient for children and teenagers [13,14]. It is believed that reducing a patient's anxiety associated with the collection of the material for assays may encourage more frequent monitoring of health conditions and diagnosis of diseases at an early stage [16].…”
Section: Introductionmentioning
confidence: 99%
“…Currently, salivary biomarkers are used for the diagnosis, prognosis, and monitoring of numerous disorders in different fields of medicine. This is possible due to the content of organic and inorganic substances that are found in the saliva [1].…”
Section: Introductionmentioning
confidence: 99%
“…However, among all of the biomarkers measured in saliva, it is the indicators of oxidative stress that are becoming increasingly popular. Interestingly, the results of recent studies indicate the high diagnostic value of salivary redox parameters in the diagnosis of obesity [19,20], insulin resistance [21,22], chronic kidney disease [23,24], but also neurodegenerative diseases (NDDs) [1,25,26]. Indeed, salivary antioxidants, as well as products of protein, lipid, and DNA oxidation, are proposed as potential diagnostic biomarkers.…”
Section: Introductionmentioning
confidence: 99%