Diagnostic imaging in the initial staging of mycosis fungoides and Sezary syndrome

Should we be imaging lymph nodes at initial diagnosis of early‐stage mycosis fungoides? Results from the PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) international study*

“…All underwent CT of the abdomen and pelvis only, and findings were normal. 6,7 The largest series of MF published so far lack any information on imaging. [8][9][10][11] It remains unclear whether imaging is useful in the management of early-stage presentation of MF and whether there are disease characteristics that should favour imaging.…”

“…The two most cited studies were published in 1986 and 1990 and included small series of patients with newly diagnosed early MF. All underwent CT of the abdomen and pelvis only, and findings were normal 6,7 . The largest series of MF published so far lack any information on imaging 8–11 .…”

Imaging Findings in a Case of Mycosis Fungoides

“…Visceral involvement is a relatively common but poorly appreciated. The lungs are the most common site of visceral involvement [3,4,5,6]. The other usual sites of extracutaneous dissemination of mycosis fungoides are liver, spleen, and blood.…”

Is PUVA maintenance therapy necessary in patients with early‐stage mycosis fungoides? Evaluation of a treatment guideline over a 28‐month follow‐up

“…Given the scarcity of extracutaneous involvement in the initial stages of MF, the use of chest x‐ray and abdominal ultrasound are sufficient in type I and II disease without lymph node involvement or other manifestations. In more advanced stages, with tumoral, erythrodermic and/or palpable lymph nodes, or in aggressive atypical forms, it is necessary to increase imaging sensibility by using computerized axial tomography (CAT) or positron emission tomography (PET) 6,14 …”