Diagnostic Criteria for Atopic Dermatitis

Williams, Hywel C

doi:10.1001/archderm.135.5.583

Cited by 43 publications

(26 citation statements)

References 24 publications

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“…showed a remarkably low sensitivity (10%) 41 . This might be due to international differences in clinical phenotype, environmental factors and observation bias 58 . Although specificity showed uniformity, sensitivity fluctuated in the population‐based studies.…”

Section: Discussionmentioning

confidence: 97%

Diagnostic criteria for atopic dermatitis: a systematic review

Brenninkmeijer¹,

Schram²,

et al. 2008

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With this systematic review of the existing sets of diagnostic criteria for AD a varying number of validation studies with varying methodological quality was found. The U.K. diagnostic criteria are the most extensively validated. However, improvement of methodological design for validation studies and uniformity in well-validated and applicable diagnostic criteria are needed to improve future intervention studies and to compare study results.

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Section: Discussionmentioning

confidence: 97%

Diagnostic criteria for atopic dermatitis: a systematic review

Brenninkmeijer¹,

Schram²,

et al. 2008

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“…The reasons for this low sensitivity are not clear, but social and cultural factors as well as translation difficulties, as discussed above, are likely to be important. Validation of the questionnaire in each country of use, and in each population sample, is desirable, and necessary if meaningful international comparisons are to be made (42).…”

Section: Discussionmentioning

confidence: 99%

Socioeconomic status and prevalence of allergic rhinitis and atopic eczema symptoms in young adolescents

Mercer

Joubert

Ehrlich

et al. 2004

Pediatric Allergy Immunology

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Environmental factors are known to influence the development of allergic rhinitis and atopic eczema in genetically susceptible individuals. Socioeconomic status (SES) may be an important indicator of risk for these conditions. The International Study of Asthma and Allergies in Childhood (ISAAC) Phase 1 written questionnaire was used to determine the prevalence and severity of allergic rhinoconjunctivitis and atopic eczema symptoms in 4947 pupils aged 13-14 years attending 30 schools in socioeconomically diverse areas of Cape Town. Home addresses were used to stratify participants into five SES bands. Relationships between symptom prevalence and severity, and SES, recent urbanization and upward socioeconomic mobility were examined. Logistic regression was used to generate odds ratios (OR) and 95% confidence intervals (CI) in order to assess overall trends by SES. The prevalences of self-reported allergic rhinitis symptoms and recurrent itchy rash in the past year were 33.2% and 11.9% respectively. Girls had a significantly higher prevalence of all symptoms than boys. The prevalence of allergic rhinitis symptoms increased from lowest to highest SES (overall OR for rhinitis symptoms in past year = 1.16, 95% CI 1.11-1.21). There was no significant trend in reported eczema symptoms by SES other than for the question, 'Have you ever had eczema' (OR = 0.88, 95% CI 0.83-0.93). Longer period of urbanization was weakly associated only with recurrent itchy skin rash (OR = 1.05, 95% CI 1.01-1.09). 'Socially mobile' pupils, i.e. those resident in the lowest SES areas but attending highest SES schools showed significantly higher prevalences of eczema and some rhinitis symptoms than pupils attending lowest SES schools. These findings may reflect differences in reporting related to language, culture and access to medical care rather than real differences in prevalence.

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“…In an editorial article, William raised several factors that could have affected the outcome of Firooz et al. ’s study, including the following [14]:…”

Section: Discussionmentioning

confidence: 99%

“…They performed a cross-sectional study looking at 416 patients (60 atopic eczema patients and 356 with other skin diseases) in a private dermatology clinic, and concluded that the UK diagnostic criteria for atopic dermatitis were not sensitive enough to be used for large population-based epidemiological studies. In an editorial article, William raised several factors that could have affected the outcome of Firooz et al's study, including the following [14]: X The criteria questions and examination protocol might not have been used as recommended. X The translation might not have followed a strict format.…”

Section: Discussionmentioning

confidence: 99%

Validation of the Chinese translated version of ISAAC core questions for atopic eczema

Chan

Pei

Krevel

et al. 2001

Clin Experimental Allergy

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SummaryBackground The International Study of Asthma and Allergies in Childhood (ISAAC) was designed to allow international comparison of epidemiological data on atopic conditions in childhood. In so doing, further aetiological information would be obtained that in turn would provide a framework for future studies. The global ISAAC results on the prevalence of atopic dermatitis indicated a 60-fold variation recorded in different countries. Such a degree of difference may be partially due to the translated questionnaires that were not validated in all of the involved countries. Objective To validate the Chinese version of the ISAAC core questions for atopic eczema. Methods One thousand nine hundred and twenty children aged between 3 and 5 were randomly recruited from 13 kindergartens in Hong Kong. Using a dermatologist's clinical examination as the gold standard, we validated the Chinese version of the ISAAC core questions for atopic eczema. The Youden's Indexes obtained in our study were compared with those obtained in the United Kingdom's validation study. Results The Youden's Indexes obtained in our study were significantly lower than those from the United Kingdom. The low scores were likely to be due to a reduction in the sensitivity of the Chinese questionnaire, which ranged from 23.5% to 70.6%. Conclusion Our findings indicate that the translated questionnaire is less effective than the English version in assessing the prevalence of atopic eczema. The indication of a low prevalence of atopic eczema among the Chinese population reported in previous studies was at least partially due to problems with the translated questionnaire.

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Diagnostic Criteria for Atopic Dermatitis

Cited by 43 publications

References 24 publications

Diagnostic criteria for atopic dermatitis: a systematic review

Diagnostic criteria for atopic dermatitis: a systematic review

Socioeconomic status and prevalence of allergic rhinitis and atopic eczema symptoms in young adolescents

Validation of the Chinese translated version of ISAAC core questions for atopic eczema

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