Diagnostic and therapeutic considerations for cutaneous Mycobacterium haemophilum infections

Chronic Cutaneous Mycobacterium haemophilum Infection Acquired from Coral Injury

“…We report a case of M. haemophilum infection occurring in an individual in good health and with no evidence of immunosuppression, to add to the handful of other cases described to date [1,2]. M. haemophilum was first described in 1978 in an Israeli patient by Sompolinsky and colleagues [3,4].…”

Cutaneous Mycobacterium haemophilum infection in iatrogenically immunocompromised patients without transplantation

“…4,13 To date, more than 100 cases of cutaneous M haemophilum infection have been reported in the literature; however, very few cases have been described in HIV-negative patients who are taking immunosuppressive medications for medical conditions other than transplantation. 14 Such immunosuppressive drugs include methotrexate, 4,15 corticosteroids, 4,5,15-17 mycophenolate mofetil, 17 and azathioprine 4 for treatment of various underlying conditions, including coronary artery disease (status postcoronary artery bypass grafting), 18 rheumatoid arthritis, 4,19 Crohn's, 4,5 pyomyositis, 16 diabetes mellitus, 20 systemic lupus erythematosis, 5,17 Sjogren's, 5 mycosis fungoides, 5 and polymyalgia rheumatica. 15 Likewise, the clinical spectrum of cutaneous M haemophilum infection is varied and may mimic cellulitis, vasculitis, panniculitis, sarcoidosis, mycosis, or chronic granulomatous inflammation.…”

Activities of antimicrobial agents against clinical isolates of Mycobacterium haemophilum

“…The most detailed descriptions of test procedures used were noted in six papers reporting the results of 18 isolates. A variety of agar methods were described in five papers (3,7,11,13,14), and a broth microdilution method was used for the sixth paper (20).…”