Diagnostic Accuracy of History, Physical Examination, Laboratory Tests, and Point‐of‐care Ultrasound for Pediatric Acute Appendicitis in the Emergency Department: A Systematic Review and Meta‐analysis

Abstract

Presence of AA is more likely in patients with undifferentiated abdominal pain migrating to the RLQ or when cough/hop pain is present in the physical examination. Once AA is suspected, no single history, physical examination, laboratory finding, or score attained on PAS can eliminate the need for imaging studies. Operating characteristics of ED-POCUS are similar to those reported for RUS in literature for diagnosis of AA. In ED patients suspected of AA, a positive ED-POCUS is diagnostic and obviates the need for CT or MRI while negative ED-POCUS is not enough to rule out AA.

sTREM-1 assessment as a diagnostic biomarker for suspected acute appendicitis in children

“…A CT examination is not as dependent on the operating technician; however it is not an optimal test due to radiation exposure. revealed that there is no single biomarker that can eliminate the need for further imaging studies [40].…”

Función del índice de volumen plaquetario medio/ linfocitos en el diagnóstico de la apendicitis durante la niñez

“…2 Si bien se han utilizado diferentes análisis de laboratorio y estudios por imágenes para llegar a un diagnóstico rápido y preciso, estos presentaban limitaciones a la hora de diferenciar la apendicitis de otras causas de dolor abdominal. 3 En el último tiempo ha habido un creciente interés en los parámetros hematológicos simples, como el volumen plaquetario medio (VPM) y el índice de plaquetas/linfocitos (IPL), que se cree que son marcadores de la gravedad de la respuesta inflamatoria sistémica. Durante el recuento de células sanguínea de rutina, los contadores hematológicos automatizados calculan y brindan recientes, se informó que la concentración de IVPML tiene implicancias clínicas en diferentes afecciones, como la inflamación sistémica, el infarto de miocardio y el compromiso de la circulación colateral coronaria.…”

Appendicitis in Children: Symptoms and Signs, Laboratory and Histopathology Findings in 67 Patients

“…Acute abdominal pain constitutes 20% of all pediatric surgery admissions [1]. Typical clinical presentation of appendicitis that includes pain, nausea, vomiting and low-grade fever sometimes accompanied by constipation or diarrhea may significantly differ in children [2]. A child may present with very few symptoms and in good general health or in very severe general condition with signs of septic shock and/or bowel obstruction.…”