Abigail Shaw, Venkat Iyer, Nick Rooney, Rebecca Wragg, Paula Waits, Eileen Roberts, Harry R. Haynes, Kathreena M. Kurian
Abstract:INTRODUCTION. Rebiopsy rates as high as 12% have been reported in previous studies of Primary Central Nervous System Lymphoma (PCNSL). This can lead to secondary operations, increasing risks of morbidity to the patient and costs for the NHS. Polymerase Chain Reaction (PCR) testing for clonality in haematological malignancies has been applied to cases of lymphoma outwith the central nervous system (CNS), but is less commonly used in the diagnosis of CNS lymphomas. Clonality in B- and T-cell populations may indi…
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