Diagnosis of concomitant inducible laryngeal obstruction and asthma

Lee, Joy W.; Tay, Tunn Ren; Paddle, Paul; Richards, Amanda L.; Pointon, Lisa; Voortman, Miriam; Abramson, Michael J.; Hoy, Ryan; Hew, Mark

doi:10.1111/cea.13185

Cited by 31 publications

(32 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…EILO was found in 35.2% ( n = 31) of the studied athletes and asthma was concurrently present in 38.7% ( n = 12) in athletes with EILO. Since asthma and laryngeal obstruction may coexist [ 59 , 61 ], it is important to remember that exercise-induced symptoms in an individual treated for asthma may not be due to bronchial obstruction but rather due to untreated laryngeal problems.…”

Section: Discussionmentioning

confidence: 99%

Asthma in Competitive Cross-Country Skiers: A Systematic Review and Meta-analysis

et al. 2020

View full text Add to dashboard Cite

Introduction In cross-country skiing, the repetitive ventilation of large amounts of cold and dry air strains the airways. The aim of this systematic review was to establish an overview of the current literature on asthma in cross-country skiers, biathletes and ski-orienteers. Methods Six databases were searched on August 29, 2019. The search yielded 2161 articles. Thirty articles fulfilled the search criteria and were pooled together for a qualitative synthesis. Eight articles were included in the meta-analysis on the prevalence of asthma and the use of asthma medication. Results According to the meta-analysis, the prevalence of self-reported physician-diagnosed asthma in skiers was 21% (95% CI 14–28%). The onset age of asthma was higher in skiers than in non-skiers with asthma. The prevalence of asthma medication use was on average 23% (CI 95% 19–26%). Several studies reported that asthma was underdiagnosed in skiers, as previously healthy skiers without a prior asthma diagnosis or medication use were frequently found to fulfill diagnostic criteria for asthma according to lung function tests. Studies using bronchial biopsy demonstrated that eosinophilic asthma is not detected in skiers with asthma as often as it is in non-skiers with asthma and that there are signs of airway inflammation even in non-asthmatic skiers. Conclusion Our findings suggest that the accuracy and coverage of diagnosing asthma in skiers has improved over the recent decades. However, the optimal treatment and natural course of asthma in this population remain unclear. Future research should investigate how the intensity of training, airway infections and their treatment affect the development of asthma among skiers. PRD registration number CRD42017070940.

show abstract

Section: Discussionmentioning

confidence: 99%

Asthma in Competitive Cross-Country Skiers: A Systematic Review and Meta-analysis

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In 2018, Lee et al revisited the difficult associations and differences between vocal cord dysfunction (perhaps better called inducible laryngeal obstruction) and asthma in 69 consecutive patients attending a “difficult asthma service” that focuses on complex comorbidities. Their main objective was to compare a questionnaire approach to diagnosis of vocal cord dysfunction with direct vocal cord visualization during a mannitol challenge.…”

Section: Asthma and Rhinitismentioning

confidence: 99%

Developments in the field of clinical allergy in 2018 through the eyes of Clinical and Experimental Allergy, Part II

Roberts

Almqvist

Boyle

et al. 2019

Clin Experimental Allergy

View full text Add to dashboard Cite

show abstract

“…It is estimated that EILO is present in 6% of adolescents and as many as one in four athletes with unexplained respiratory symptoms [1, 2]. Despite improved recognition over the past 5 years [3, 4], it remains frequently misdiagnosed and mistreated as asthma [2, 5].…”

mentioning

confidence: 99%

“…The CLE test has now been performed in many thousands of cases worldwide and is a key step in providing robust diagnosis, but also in permitting characterisation of an individual's EILO, i.e. to differentiate glottic versus supraglottic level closure [5]. The latter may dictate the choice of optimal management strategy, which can include surgical intervention in selected cases [7].…”

mentioning

confidence: 99%

Feasibility of portable continuous laryngoscopy during exercise testing

Hull¹,

Walsted²,

Orton³

et al. 2019

ERJ Open Res

View full text Add to dashboard Cite

Exercise-induced laryngeal obstruction (EILO) is a prevalent and yet still under-recognised cause of exertional breathlessness [1]. The transient closure of the larynx, which develops during EILO, results in dyspnoea, cough, inspiratory wheeze (i.e. stridor) and tightness in the throat on physical exertion. It is estimated that EILO is present in 6% of adolescents and as many as one in four athletes with unexplained respiratory symptoms [1, 2]. Despite improved recognition over the past 5 years [3, 4], it remains frequently misdiagnosed and mistreated as asthma [2, 5].

show abstract

Diagnosis of concomitant inducible laryngeal obstruction and asthma

Cited by 31 publications

References 42 publications

Asthma in Competitive Cross-Country Skiers: A Systematic Review and Meta-analysis

Asthma in Competitive Cross-Country Skiers: A Systematic Review and Meta-analysis

Developments in the field of clinical allergy in 2018 through the eyes of Clinical and Experimental Allergy, Part II

Feasibility of portable continuous laryngoscopy during exercise testing

Contact Info

Product

Resources

About