Diagnosis and management of prolactinomas and non-functioning pituitary adenomas

Rogers, Alice; Karavitaki, Niki; Wass, John

doi:10.1136/bmj.g5390

Cited by 35 publications

(22 citation statements)

References 29 publications

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“…At the present time, NFPA are diagnosed either in the context of mass effect related to the growth of a macroadenoma or, increasingly, fortuitously during imaging for some unrelated purpose; the latter case is known as pituitary incidentaloma [7,8].…”

mentioning

confidence: 99%

Management of clinically non-functioning pituitary adenoma

Chanson

Raverot

Castinetti

et al. 2015

Annales d'Endocrinologie

151

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Clinically NFPA is currently the preferred term for designing all the pituitary adenomas which are not hormonally active (in other words, not associated with clinical syndromes such as amenorrhea-galactorrhea in the context of prolactinomas, acromegaly, Cushing's disease or hyperthyroidism secondary to TSH-secreting adenomas). They account for 15-30% of pituitary adenomas. Diagnosis is usually made either in the context of mass effect due to a macroadenoma or, increasingly, fortuitously during imaging performed for some unrelated purpose; the latter case is known as pituitary incidentaloma. Surgery is indisputably indicated in case of tumoral syndrome, but other aspects of NFPA (hormonal work-up, follow-up, and especially postoperative follow-up, management of remnant or recurrence, the special case of incidentaloma, or apoplexy) remain controversial. The French Endocrinology Society (SFE) therefore set up an expert working group of endocrinologists, neurosurgeons, ophthalmologists, neuroradiologists, pathologists and biologists to draw up guidelines, at the 2012 SFE Congress in Toulouse, France. The present article presents the guidelines suggested by this group of French-speaking experts.

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mentioning

confidence: 99%

Management of clinically non-functioning pituitary adenoma

Chanson

Raverot

Castinetti

et al. 2015

Annales d'Endocrinologie

151

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“…Prolactinomas account for 57% of pituitary tumours 1. Female patients with prolactinoma typically present with menstrual irregularities and galactorrhoea; however, galactorrhoea may be absent in patients with severe hypogonadism, as seen in our present case 2.…”

Section: Descriptionmentioning

confidence: 44%

A giant prolactinoma with nasopharyngeal extension presenting with nasal blockage and epistaxis

et al. 2015

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“…Dentro de las modalidades y abordajes quirúrgicos, la cirugía endoscópica endonasal transesfenoidal es el mejor tipo de abordaje; la mortalidad de esta cuando es realizada por un neurocirujano experto es menor al 1%. No obstante, se han observado complicaciones intraoperatorias como hipotensión ortostática (1,9%) y pérdida sanguínea con requerimiento de transfusión (2,9%); así como complicaciones a los 30 días, como diabetes insípida transitoria (9,6%), secreción inadecuada de hormona antidiurética (8,7%) y escape de líquido cefalorraquídeo que requiere drenaje lumbar (0,9%) (45). Se ha encontrado frecuencia de recidiva entre el 15% y el 66% después de la cirugía y entre el 2% y el 28% posterior a la cirugía con radioterapia adyuvante (46,47).…”

Section: Tumores Pituitariosunclassified

Epidemiología y caracterización general de los tumores cerebrales primarios en el adulto

Gómez-Vega¹,

Ocampo-Navia²,

Lee³

2018

UNIV.MED.

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Los tumores primarios del sistema nervioso representaron aproximadamente el 1,4 % de los nuevos diagnósticos de cáncer en 2015 y causan el 2,6 % de las muertes por cáncer. Estos tienen una mayor implicación clínica en la población infantil y en adultos jóvenes; y su incidencia disminuye con la edad. Los tumores más frecuentes en los adultos incluyen meningiomas, gliomas y tumores pituitarios. En este artículo se hace una revisión actualizada sobre la epidemiología de los tumores primarios del sistema nervioso, así como las principales características y actualizaciones en el manejo de los tumores más prevalentes en la población adulta.

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Diagnosis and management of prolactinomas and non-functioning pituitary adenomas

Cited by 35 publications

References 29 publications

Management of clinically non-functioning pituitary adenoma

Management of clinically non-functioning pituitary adenoma

A giant prolactinoma with nasopharyngeal extension presenting with nasal blockage and epistaxis

Epidemiología y caracterización general de los tumores cerebrales primarios en el adulto

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