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Cited by 637 publications
(488 citation statements)
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References 136 publications
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“…Brucella spp. endocarditis (BE) is an uncommon infection of the cardiovascular system, but it is one of the most challenging complications of brucellosis [3,4]. Brucella melitensis is highly virulent and associated with a severe clinical course, particularly endocarditis.…”
Section: Introductionmentioning
confidence: 99%
“…Brucella spp. endocarditis (BE) is an uncommon infection of the cardiovascular system, but it is one of the most challenging complications of brucellosis [3,4]. Brucella melitensis is highly virulent and associated with a severe clinical course, particularly endocarditis.…”
Section: Introductionmentioning
confidence: 99%
“…[5] The central nervous system is the most common site for embolic events, with up to 65% occurring there. [4]…”
Section: Discussionmentioning
confidence: 99%
“…The spleen is vulnerable to infarction because it lacks collateral circulation, and splenic infarction occurs in approximately 40% of left-sided IE cases. [4,6] Localized findings are absent in 90% of splenic infarcts and abscesses. [2,7] It has been estimated that approximately 5% of patients with splenic infarction will develop splenic abscess.…”
Section: Discussionmentioning
confidence: 99%
“…High doses of antibiotics are needed. Prolonged parenteral administration of a bactericidal antimicrobial agent or a combination of agents is currently recommended (1,(10)(11)(12). The initial treatment usually cannot await blood culture results when the symptoms progressively worsen, so the physician must choose drugs to cover the species of organisms most likely to be present.…”
Section: Discussionmentioning
confidence: 99%