Infectious Disease Clinics of North America volume 21, issue 1, P19-48 2007 DOI: 10.1016/j.idc.2007.01.008 View full text
Nicola M. Zetola, Christopher D. Pilcher

Abstract: HIV infection starts as an acute, systemic infection, followed by a chronic period of clinical latency, usually lasting 3 to 10 years, which precedes the eventual collapse of the immune system. It is increasingly recognized that events occurring during acute HIV infection may determine the natural course of the disease. The very dynamic events of acute HIV infection provide multiple opportunities for biologic interventions, such as anti-retroviral or immune-based therapies. Similarly, the implementation of pub…

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