“…12,16,42,43 Neuropathic pain in patients with TIND may progressively alleviate in a few weeks or in up to 36 months; 30,41 however, it is necessary to start analgesic therapy to reduce pain. 10,[48][49][50] In some cases, TIND pain is much more severe than that of DN, so singleagent therapy may be maximised, or a second or a third drug may be added to analgesic therapy. 47,51 A poor response to opioids has been observed; 13 however, should pain persist, these drugs could be used additionally to other compounds.…”