Diabetes and Psoriasis

Gibson, Smith H.; Perry, Harold O.

doi:10.1001/archderm.1956.01550110031009

Cited by 21 publications

(8 citation statements)

References 7 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The risk of diabetes among individuals with psoriasis has been shown in cross-sectional studies to be elevated with RR between 1.27 and 2.48 [4, 10, 13, 14, 22-25], consistent with our prospective study. Although obesity and the metabolic syndrome had been proposed as an explanation for this increased risk [5], we found that the risk of diabetes was independent of BMI.…”

Section: Discussionsupporting

confidence: 91%

See 1 more Smart Citation

Psoriasis and the Risk of Diabetes and Hypertension

Qureshi¹,

Choi²,

Setty³

et al. 2009

Arch Dermatol

229

200

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 91%

“…Previous cross-sectional studies have demonstrated that individuals with psoriasis have a higher prevalence of obesity, diabetes and hypertension [10, 11]. Participants with mild psoriasis had a slightly, but significantly higher adjusted (for age, sex, and BMI) odds of diabetes 1.13 and hypertension 1.03 [12].…”

Section: Introductionmentioning

confidence: 99%

Psoriasis and the Risk of Diabetes and Hypertension

Qureshi¹,

Choi²,

Setty³

et al. 2009

Arch Dermatol

229

200

View full text Add to dashboard Cite

“…Gibson et al, 118 in 1956, reported the association between T2DM and psoriasis for the first time. Since then, numerous studies have reported a higher risk, with a relative risk between 1.27 and 2.48.…”

Section: Diabetes Mellitusmentioning

confidence: 99%

Metabolic and Cardiovascular Comorbidities in Psoriasis: Revisited

Basavaraj¹

2015

MGM Journal of Medical Sciences

View full text Add to dashboard Cite

There is increasing awareness that psoriasis, as a disease, is more than 'skin deep' and associated with comorbidities that potentially increase morbidity and mortality, and lower qua lity of life. The consistency of association and the diversity of comor bidities reported in psoriasis warrants it to be labeled as a complex syndrome. Merely finding an association between psoriasis and comorbidities is not going to suffice until this evi dence is put into clinical practice. The pathogenesis of pso riasis and its comorbidities is complex but several stu dies have revealed certain mechanisms and factors which are common to both. These shared pathogenic mechanisms solve the mystery to this comorbid association, especially with meta bolic syndrome and cardiovascular disease. Studying these pathogenic links may reveal certain parameters which can be utilized as potential biomarkers in the presumptive screening of patients for the presence of comorbidities. These shared pathogenic mechanisms hold the key toward establishing a novel biomarker which can monitor both the disease seve rity and the associated comorbidity. Psoriasis patients with comor bidities also incur more healthcare costs, than those without comorbidities. Cardiovascular comorbidity in psoriasis incurs the greatest increase in healthcare resource use. Early detection of cardiovascular and other comorbid conditions in pso riasis can possibly reduce the morbidity, mortality, and economic burden associated with the disease. We attempt to review the pathogenic links between psoriasis and its meta bolic and cardiovascular comorbidities.

show abstract

“…Glucose intolerance, diabetes, and obesity are more frequent in patients with psoriasis [74,75,[116][117][118][119]. The study conducted by Onsun et al has found that diabetes was significantly more frequent in patients with psoriasis when compared to the incidence of psoriasis in patients with diabetes [120].…”

Section: The Impaired Glucose Tolerance and Diabetesmentioning

confidence: 99%

Psoriasis and Genetics

Merve¹,

Sevilay²,

Oymak³

et al. 2017

An Interdisciplinary Approach to Psoriasis

View full text Add to dashboard Cite

Psoriasis is an erythematous, scaly chronic inflammatory dermatosis and occurs due to altered epidermal differentiation and hyperproliferation due to faulty signals that speed up the growth cycle of skin cells. Psoriasis reduces quality of life, and psoriatic patients generally have higher risk for metabolic disease. Psoriasis is associated with many burdening comorbidities, which often share similar pathogenic features and follow a progressive pattern. Genetic variation in human genome causes specific kind of disease, and nowadays, research is focused on metabolic pathways that trigger psoriasis and related comorbidities. In addition, genetic variations are also important for psoriasis treatment regime and response. The purpose of this section is to shown to genetic epidemiology, pharmacogenetics, immune genetics of psoriasis and related comorbidities.

show abstract

Diabetes and Psoriasis

Cited by 21 publications

References 7 publications

Psoriasis and the Risk of Diabetes and Hypertension

Psoriasis and the Risk of Diabetes and Hypertension

Metabolic and Cardiovascular Comorbidities in Psoriasis: Revisited

Psoriasis and Genetics

Contact Info

Product

Resources

About