Developmental psychopharmacology

Delirium in an Adolescent Patient during Treatment with Cephalexin

“…First, children and adolescents are supposed to be more vulnerable than adults to some toxic effects of drugs in the CNS [6]. The reason for this is unclear.…”

“…The reason for this is unclear. The developmental specificity of a drug response in the CNS is probably the result of multiple interacting factors, such as the status of various neurotransmitter systems, efficiency of feedback regulation of neuronal homeostasis, metabolic enzymes, and the function of the blood-brain barrier [6].…”