J. Clin. Lab. Anal. volume 30, issue 1, P84-89 2014 DOI: 10.1002/jcla.21820 View full text
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Chonlaphat Sukasem, Chalirmporn Atasilp, Pichai Chansriwong, Montri Chamnanphon, Apichaya Puangpetch, Ekapob Sirachainan

Abstract: We developed a rapid, reliable, more cost-effective, and simple assay to detect UGT1A1 genetic polymorphisms in routine practice before initiating irinotecan therapy. The UGT1A1*28 and UGT1A1*6 alleles were found to be similar in the Asian populations.