volume 30, issue 1, P6-12 2015
DOI: 10.1590/s0102-86502015001000002
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Abstract: ABSTRACT PURPOSE:To present a rat model of subcutaneous endometriosis for the study of pathophysiology and the effects of drugs. METHODS:Fifty three-month-old female Wistar rats (Rattus norvergicus) were distributed into one control group and four treatment groups: estradiol (2.5; 5; 10mg/kg sc), medroxyprogesterone acetate (0.5; 2; 5mg/kg sc), triptorelin pamoate (0.18; 0.56mg/kg sc) and acetylsalicylic acid (3mg/kg per os). The animals were autoimplanted subcutaneously with 4x4-mm uterine fragments to induc…

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