Development of a new antibacterial biomaterial by tetracycline immobilization on calcium-alginate beads

Ozseker, Emine Erdogan; Akkaya, Alper

doi:10.1016/j.carbpol.2016.05.073

Cited by 35 publications

(12 citation statements)

References 30 publications

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“…Sodium alginate is a biopolymer often used for immobilization of cells and encapsulation in biomedical, food, and biotechnology areas (Goh, Heng, & Chan, ; Ozseker & Akkaya, ; Qader & Aman, ; Wang, Chen, Wang, & Xing, ; Zhang, Zhang, Zou, & McClements, ). The dripping process has been proved to be the most versatile technique to enable application of sodium alginate.…”

Section: Introductionmentioning

confidence: 99%

An investigation of operational parameters of jet cutting method on the size of Ca‐alginate beads

Paulo

Ramos

Prata

2017

J Food Process Engineering

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A rarely used option for reduction the size of Ca‐alginate beads is the jet cutter, a rotating disk coupled to the output of the nozzle, and responsible for cutting the jet in smaller sizes. There are few systematic studies in the literature about this apparatus and its operational effects on the bead size. Therefore, this work aimed to investigate some operational parameters on the size of Ca‐alginate beads produced by dripping and jet cutting methods. First, physicochemical properties of different concentrations of sodium alginate solutions were determined, and the viscosity of 0.92 Pa s, corresponding to 2% (wt/wt), was found to be optimum for bead formation. For the dripping process, the highest flow rate of the alginate solution (49 mL/min) caused a limited reduction of bead size to 2 mm. This study on drop formation demonstrated that models developed for size prediction cannot be used as a tool for determination of size, due to the possible influences of the viscous forces. The jet cutter, adapted to a continuous jet regime, allowed to reduce from 5.2 mm to less than 1 mm in size with the increase of the rotation speed from 200 to 900 rpm. However, this increase resulted in higher tangential velocity of the beads, requiring larger collect recipients. This study developed the basis for broadening the application of the jet cutter to different biopolymers and ensures a better performance of this system. Practical applications The technology of microencapsulation consists in the incorporation of a compound within a matrix, and it has been often used in the food industry by solving several limitations, allowing the immobilization, protection, controlled release of some ingredients, and changing of product properties. The use of biopolymers, such as sodium alginate, associated with the dripping method, enable the preservation even thermolabile compounds, such as drugs, organisms, proteins, and fragrances, since mild conditions are used. However, large beads are produced, which can limit their application. A rarely used and cost‐effective option for size reduction is the jet cutter, a cutting tool that, during its rotation, breaks the jet in smaller sizes, producing very small beads. The results of this study showed that the use of jet cutter was effective in the reduction of bead size and developed some basis for broadening its application for encapsulation using different materials.

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Section: Introductionmentioning

confidence: 99%

An investigation of operational parameters of jet cutting method on the size of Ca‐alginate beads

Paulo

Ramos

Prata

2017

J Food Process Engineering

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“…The peak at 1632 cm −1 was attributed to the presence of peptide bond formation between free single bond CHO group of glutaraldehyde and the amide group of protein [37]. The peak at 1105 cm −1 indicated the C-N bond presented in the amide bond [38]. These adsorption peaks indicated that BSA was immobilized on MN.…”

Section: Resultsmentioning

confidence: 99%

Rapid Screening and Identification of BSA Bound Ligands from Radix astragali Using BSA Immobilized Magnetic Nanoparticles Coupled with HPLC-MS

et al. 2016

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Radix astragali is widely used either as a single herb or as a collection of herbs in a complex prescription in China. In this study, bovine serum albumin functionalized magnetic nanoparticles (BSA-MN) coupled with high performance liquid chromatography-mass spectrometry (HPLC-MS) were used to screen and identify bound ligands from the n-butanol part of a Radix astragali extract. The prepared BSA-MN showed sufficient magnetic response for the separation with an ordinary magnet and satisfied reusability. Fundamental parameters affecting the preparation of BSA-MN and the screening efficiency were studied and optimized. Under the optimum conditions, four bound ligands were screened out from the n-butanol part of a Radix astragali extract and identified as genistin (1), calycosin-7-O-β-D-glucoside (2), ononin (3) and formononetin (4). This effective method could be widely applied for rapid screening and identification of active compounds from complex mixtures without the need for preparative isolation.

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“…The band at 1730 cm −1 corresponded to the carbonyl C = O group [17], while the band at 889 cm −1 was ascribed to the amide vibration. The peak, which appeared at 1248 cm −1 , was the (C-O-C) stretching vibration of sodium alginate, and was due to its saccharide structure [18].…”

Section: Fourier Transforms Infra-red (Ft-ir) Spectroscopymentioning

confidence: 99%

Synthesis and application of alginate immobilised banana peels nanocomposite in rare earth and radioactive minerals removal from mine water

Oyewo

Wolkersdorfer

2019

IET nanobiotechnol.

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This study describes the preparation, characterisation and application of pelletised immobilised alginate/ montmorillonite/banana peels nanocomposite (BPNC) in a fixed-bed column for continuous adsorption of rare earth elements and radioactive minerals from water. The materials was characterised by Fourier transform infrared, X-ray diffraction and scanning electron microscopy analyses. Analyses indicated that the pellets are porous and spherical in shape. FT-IR analysis showed that the functional groups responsible for the coordination of metal ions were the carboxylic (-COO-) and siloxane (Si-O-Si and Si-O-Al) groups. XRD analysis showed two additional peaks which were attributed to alginate and montmorillonite. The influence of the initial concentration, bed depth and flow rate were investigated using synthetic and real mine water in order to determine the breakthrough behaviour of both minerals. The processed bed volume, adsorbent exhaustion rate and service time, were also explored as performance indices for the adsorbent material. Furthermore, the breakthrough data were fitted to both the Thomas and Bohart-Adams models. The BPNC exhibited high affinity for U, Th, Gd and La in the real mine water sample. However, studies may still be required using waters from different environments in order to determine the robustness of BPNC.

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Development of a new antibacterial biomaterial by tetracycline immobilization on calcium-alginate beads

Cited by 35 publications

References 30 publications

An investigation of operational parameters of jet cutting method on the size of Ca‐alginate beads

An investigation of operational parameters of jet cutting method on the size of Ca‐alginate beads

Rapid Screening and Identification of BSA Bound Ligands from Radix astragali Using BSA Immobilized Magnetic Nanoparticles Coupled with HPLC-MS

Synthesis and application of alginate immobilised banana peels nanocomposite in rare earth and radioactive minerals removal from mine water

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