volume 76, issue 3, P251-256 2007
DOI: 10.5025/hansen.76.251
View full text

Abstract: As the number of whole genome sequences available continues to increase rapidly, the raw scale of the sequence data being used in analysis is the first hurdle for comparative genome analysis. When performing whole genome alignments, large-scale rearrangements make it necessary to first find out roughly which short well-conserved segments correspond to what other segments (termed anchors). Successful results have been achieved by adapting tools like BLAT and BLASTZ on a problem-to-problem basis, but the work re…

expand abstract