Development of a cost-effective multiplex quantitative RT-PCR assay for early detection and surveillance of Dengue, Chikungunya, and co-infections from clinical samples in low-resource settings
Shruthi Uppoor,
Samruddhi Walaskar,
Ritika Majji
et al.
Abstract:BackgroundDengue and Chikungunya are Aedes-borne diseases that are predominantly prevalent in tropical and subtropical regions, affecting public health globally. Dengue is caused by multiple antigenically different Dengue virus (DENV) serotypes (DENV-1 to DENV 4) in the Flaviviridae family and Chikungunya (CHIKV) in the Togaviridae family. Both viral diseases produce similar clinical manifestations, especially in the early stages of infection which poses a significant challenge for timely diagnosis and imprope… Show more
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