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“…The clinical trial was registered as “Targeted Levothyroxine Dosing in Infants with Congenital Hypothyroidism” (NCT02374593 at https:// www.clinicaltrials.gov). Per our standard protocol, all subjects were started on LT4 10 to 15 mcg/kg/day by their primary care provider in consultation with the coordinator for the Indiana Newborn Screening Follow-up Program (EAE) as soon as confirmatory serum testing was drawn or had resulted (10). LT4 was prescribed as oral tablets, and parents were instructed to crush the tablet; mix it with a small amount of water, breastmilk, or formula; and give it to the infant using an oral medication syringe.…”
Section: Methodsmentioning
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“…The clinical trial was registered as “Targeted Levothyroxine Dosing in Infants with Congenital Hypothyroidism” (NCT02374593 at https:// www.clinicaltrials.gov). Per our standard protocol, all subjects were started on LT4 10 to 15 mcg/kg/day by their primary care provider in consultation with the coordinator for the Indiana Newborn Screening Follow-up Program (EAE) as soon as confirmatory serum testing was drawn or had resulted (10). LT4 was prescribed as oral tablets, and parents were instructed to crush the tablet; mix it with a small amount of water, breastmilk, or formula; and give it to the infant using an oral medication syringe.…”
Section: Methodsmentioning