Abstract:A simple, precise and rapid reverse phase HPLC-PDA method has been developed and validated for the simultaneous analysis of hydroquinone (HYQ), dexamethasone (DEX), triamcinolone acetonide (TSA), hydrocortisone acetate (HYA), betamethasone valerate (BEV) and retinoic acid (REA) in the cream dosage form. The mixture of HYQ, DEX, TSA, HYA, BEV and REA was separated on Waters X Bridge C18 5 μm column (4.6 mm × 250 mm). All separations were performed with a 2998 Photodiode Array (PDA) detector on 210-400 nm wavele… Show more
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