Development and Dosimetric Characterization of a Customizable Shield for Subtotal Skin Electron Beam Therapy

Lucido, J.; Penoncello, Gregory P.; Laughlin, Brady S; Armstrong, Michael F.; Lo, Stephanie; Rivera, Judith N.; Tang, Xueyan; Chungbin, Suzanne; Breen, William; Mangold, Aaron R.; Comfere, Nneka I.; Lester, Scott C.; Rule, William G.; Deufel, Christopher L.; Foster, Madeline G.

doi:10.1016/j.adro.2023.101289

Cited by 1 publication

(5 citation statements)

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“…The limitations in shielding techniques prompted us to design and build a customizable STSEBT shielding system that is professional in appearance, allows for adjustable treatment window dimensions, is non-toxic, transparent, portable, and easy to disinfect in a hospital environment. Such a design was not available commercially (5). In collaboration with Radiation Products Design, we designed and built a universal STSEBT shielding stand.…”

Section: Methodsmentioning

confidence: 99%

“…It consists of a mobile frame that can accommodate a tall stack of acrylic shielding slats. The stacked slat technique serves multiple functions: each 10 cm-tall piece is relatively lightweight, and it allows for flexibility in treatment window design (5). The tops and bottoms of the slats are ship-lapped, such that they interlock with the slats above and below them, promoting a tight and overlapping fit, minimizing leakage dose from between adjacent slats (5).…”

Section: Methodsmentioning

confidence: 99%

“…The stacked slat technique serves multiple functions: each 10 cm-tall piece is relatively lightweight, and it allows for flexibility in treatment window design (5). The tops and bottoms of the slats are ship-lapped, such that they interlock with the slats above and below them, promoting a tight and overlapping fit, minimizing leakage dose from between adjacent slats (5). The frame allows for mounting of slats in a variety of vertical positions, with the ability to hold a tall stack of slats up from the bottom for a lower extremity treatment.…”

Section: Methodsmentioning

confidence: 99%

“…The frame allows for mounting of slats in a variety of vertical positions, with the ability to hold a tall stack of slats up from the bottom for a lower extremity treatment. The dimensions are appropriate to provide stability for a fully loaded frame (5).…”

Section: Methodsmentioning

confidence: 99%

“…6,51.5%], 36.8% [IQR=20, 68%] at six months, and 57.9% [IQR=38. 5,87.1%] at one year. Low rates of toxicities were recorded.…”

mentioning

confidence: 99%

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Tailoring Radiation Therapy for Patients With Limited Cutaneous T Cell Lymphoma: Preliminary Clinical Experience With Subtotal Skin Electron Therapy

LAUGHLIN,

ZANILETTI,

FOSTER

et al. 2024

Anticancer Res

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Background/Aim: Total skin electron beam therapy (TSEBT) is an effective treatment for managing cutaneous Tcell lymphoma (CTCL), but may result in unnecessary toxicity. With the production of a custom rolling shield holding a configurable stack of plastic slats to block uninvolved skin, we implemented a program for subtotal skin electron beam therapy (STSEBT). We report our preliminary experience with STSEBT vs. TSEBT to manage CTCL. Patients and Methods: A retrospective review of 32 CTCL patients who were treated at a single institution between February 28th, 2017, and May 25th, 2022, was completed. Of these cases, seven patients received STSEBT and 25 received TSEBT. Results: Thirty-two patients underwent a course of STSEBT or TSEBT. The median follow-up was 465 days and the median age at diagnosis was 70.8 years. Stage distribution was as follows: one (3%) IA, 16 (50%) IB, 6 (19%) IIB, two (6%) IIIA, five (16%) IVA, and two (6%) IVB. The overall response rate was 96%. For patients receiving TSEBT (n=25), three (12%), 10 (40%), and 11 (44%) had a CR, NCR, and PR, respectively.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%