Determination of uncertainties associated to the in vivo measurement of iodine-131 in the thyroid

Dantas, Bernardo Maranhão; Lima, F. F.; Dantas, Ana Letícia Almeida; Lucena, Evandro; Gontijo, Rodrigo Modesto Gadelha; Carvalho, Carlos Brian Oliveira de; Hazin, C.A.

doi:10.1016/j.apradiso.2016.04.007

Cited by 7 publications

(2 citation statements)

References 1 publication

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“…The uncertainty associated with CC was used to calculate the MDA of ISO 11929 (5). The value of the CC and its uncertainty can vary considerably depending on the radionuclide activity in the phantom at the time of measurement (17). Thus, three different phantom activity ranges were established to the calculation of the mean CC and it's respective uncertainty: i) activities in the phantom below 300Bq; ii) activities in the phantom above 300 Bq; and iii) full range of activities.…”

Section: Methodsmentioning

confidence: 99%

Comparação entre diferentes metodologias para a determinação da atividade mínima detectável dos sistemas de dosimetria interna in vivo

Vital

Mendes²,

Silva³

et al. 2022

Rev Bras Fis Med

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A atividade mínima detectável (AMD) representa o valor mínimo de atividade que é detectada em um sistema de monotoração. Existem diversas metodologias que podem ser utilizadas para calcular a AMD, no entanto os resultados para cada uma destas podem ser divergentes. Laboratórios de dosimetria interna in vivo devem dispor deste parâmetro para cada tipo de geometria de contagem, bem como, para cada tipo de radionuclídeo de interesse, visando a otimização do processo de monitoração interna. O objetivo deste trabalho foi comparar três tipos de metodologias de cálculo utilizadas na determinação da AMD com os resultados obtidos experimentalmente. As metodologias de cálculo utilizadas foram as sugeridas por Currie (1968), a publicada em Health Physics Society N13.30 (1996) e a ISO 11929 (2018). A monitoração de um phantom de cabeça contendo na região correspondente ao cérebro 18F-FDG foi realizada para a obtenção da AMD experimental. Os resultados obtidos para os valores de AMDs utilizando as três diferentes metodologias apresentaram diferenças de acordo com as faixas de atividades analisadas. As incertezas do fator de calibração e Background do sistema são os principais parâmetros entre as três metodologias de cálculo que influenciaram nos resultados obtidos.

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Section: Methodsmentioning

confidence: 99%

Comparação entre diferentes metodologias para a determinação da atividade mínima detectável dos sistemas de dosimetria interna in vivo

Vital

Mendes²,

Silva³

et al. 2022

Rev Bras Fis Med

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“…131 I is widely used for diagnostic [3] and therapeutic [4] purposes. For many decades, radioactive iodine was orally administered to patients for the treatment of benign and malignant thyroid diseases [5][6][7][8][9]. Indeed, a major part of the administered radioiodine will concentrate in the thyroid gland; the emitted βparticles of short ranges will only damage thyroid cells without any harmful health effects to the neighboring organ tissues.…”

Section: Introductionmentioning

confidence: 99%

Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of <sup>131</sup>I by Patients

Misdaq¹,

Harrass²,

Karime³

et al. 2016

AJEP

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Total activities due to the ingestion of 131 I were evaluated in different compartments of the human body of patients. It has been shown that the 131 I activity in urine of patients increases when the 131 I uptake decreases which could represent a source of radiation for their relatives when they leave hospitals. A new dosimetric model based on the specific betadose concept was developed for evaluating committed equivalent doses to thyroid due to 131 I uptake by different age groups of patients. Data obtained are in good agreement with those obtained by using the ICRP model for iodine. Committed equivalent dose to the thyroid gland is influenced by the mass of thyroid, 131 I uptake and energy of the emitted beta particles. In addition, 131 I uptake was measured by using a gamma camera and committed equivalent doses to the thyroid gland of female patients from the ingestion of 131 I for the treatment of hyperthyroidism diseases were evaluated. Data obtained by using our model and the ICRP ingestion dose coefficients are in good agreement with each other.

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Experience and performance of In Vivo Monitoring Laboratory of NIRP in 2017 thyroid measurement intercomparison

Peng

Zhang

et al. 2021

Applied Radiation and Isotopes

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Determination of uncertainties associated to the in vivo measurement of iodine-131 in the thyroid

Cited by 7 publications

References 1 publication

Comparação entre diferentes metodologias para a determinação da atividade mínima detectável dos sistemas de dosimetria interna in vivo

Comparação entre diferentes metodologias para a determinação da atividade mínima detectável dos sistemas de dosimetria interna in vivo

Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of <sup>131</sup>I by Patients

Experience and performance of In Vivo Monitoring Laboratory of NIRP in 2017 thyroid measurement intercomparison

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Determination of uncertainties associated to the in vivo measurement of iodine-131 in the thyroid

Cited by 7 publications

References 1 publication

Comparação entre diferentes metodologias para a determinação da atividade mínima detectável dos sistemas de dosimetria interna in vivo

Comparação entre diferentes metodologias para a determinação da atividade mínima detectável dos sistemas de dosimetria interna in vivo

Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of &lt;sup&gt;131&lt;/sup&gt;I by Patients

Experience and performance of In Vivo Monitoring Laboratory of NIRP in 2017 thyroid measurement intercomparison

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Determination of Beta Radiation Dose to the Thyroid Gland from the Ingestion of <sup>131</sup>I by Patients