Determination of the Thermal Decomposition Products of Terephthalic Acid by Using Curie-Point Pyrolyzer

Kimyonok, Alpay; Ulutürk, Mehmet

doi:10.1080/07370652.2015.1005773

Cited by 34 publications

(17 citation statements)

References 11 publications

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“…A DSC analysis of ITR and TER on their own showed that the drug melted at around 166 °C [ 12 ], while TER melted with sublimation at around 350 °C [ 29 ] ( Figure 3 ). A thermal analysis of the binary ITR–TER mixtures post-processing showed thermograms with a sharp endothermic peak at 198 °C ( Figure 3 ), which was absent in the parent compounds and indicated the melting of the new phase.…”

Section: Resultsmentioning

confidence: 99%

Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal

Cruz

Boleslavská

Beránek³

et al. 2020

Pharmaceutics

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The crystallization of poorly soluble drug molecules with an excipient into new solid phases called cocrystals has gained a considerable popularity in the pharmaceutical field. In this work, the cocrystal approach was explored for a very poorly water soluble antifungal active, itraconazole (ITR), which was, for the first time, successfully converted into this multicomponent solid using an aromatic coformer, terephthalic acid (TER). The new cocrystal was characterized in terms of its solid-state and structural properties, and a panel of pharmaceutical tests including wettability and dissolution were performed. Evidence of the cocrystal formation was obtained from liquid-assisted grinding, but not neat grinding. An efficient method of the ITR–TER cocrystal formation was ball milling. The stoichiometry of the ITR–TER phase was 2:1 and the structure was stabilized by H-bonds. When comparing ITR–TER with other cocrystals, the intrinsic dissolution rates and powder dissolution profiles correlated with the aqueous solubility of the coformers. The rank order of the dissolution rates of the active pharmaceutical ingredient (API) from the cocrystals was ITR–oxalic acid > ITR–succinic acid > ITR–TER. Additionally, the ITR–TER cocrystal was stable in aqueous conditions and did not transform to the parent drug. In summary, this work presents another cocrystal of ITR that might be of use in pharmaceutical formulations.

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Section: Resultsmentioning

confidence: 99%

Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal

Cruz

Boleslavská

Beránek³

et al. 2020

Pharmaceutics

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“…This observation can be supported by the purely ionic character of the coordination bond in Li-NTA and the known decomposition of terephthalic acid at elevated temperatures. 44 The presence of a dissociating group facilitates the disruption of the coordination network and leads to decomposition into carbonaceous material. Thus, Li-NTA-C presents an energy efficient approach to obtain ordered carbonaceous matrices from higher dimensional supramolecular architectures of purely ionic solids.…”

Section: Resultsmentioning

confidence: 99%

Conversion of a microwave synthesized alkali-metal MOF to a carbonaceous anode for Li-ion batteries

et al. 2020

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“…This benzoic acid is either turned into phenol by elimination of CO or benzaldehyde by elimination of OH. These phenols and aldehydes are can thermally decompose to simpler mono-aromatic ringed compounds like toluene or styrene or complex multi-ringed compounds like 1,1-biphenyl or benzophenone by polymerization of some radicals [52]. This decomposition and formation of hydrocarbons is further catalyzed by the MnO 2 nano-particles anchored on the graphene substrates [53].…”

Section: Resultsmentioning

confidence: 99%

Metal Organic Framework Derived MnO2-Carbon Nanotubes for Efficient Oxygen Reduction Reaction and Arsenic Removal from Contaminated Water

et al. 2020

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Even though manganese oxides are attractive materials for batteries, super-capacitors and electro-catalysts for oxygen reduction reactions, in most practical applications MnO2 needs to be hybridized with conductive carbon nano-structures to overcome its inherent poor electrical conductivity. In this manuscript we report microwave-assisted synthesis of MnO2 embedded carbon nanotubes (MnO2@CNT) from Mn-H3BTC (benzene-1,3,5-carboxylic acid) metal organic frameworks (MOF) precursors. Using graphene oxide as microwave susceptible surface, MnO2 nano-particles embedded in three dimensional reduced graphene oxide (rGO) -CNT frameworks (MnO2@CNT-rGO) were synthesized which when applied as electro-catalysts in oxygen reduction reaction (ORR) demonstrated comparable half-wave potential to commercial Pt/C, better stability, and excellent immunity to methanol crossover effect in alkaline media. When carbon fiber (CF) was used as substrate, three-dimensional MnO2@CNT-CF were obtained whose utility as effective adsorbents for arsenic removal from contaminated waters is demonstrated.

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Determination of the Thermal Decomposition Products of Terephthalic Acid by Using Curie-Point Pyrolyzer

Cited by 34 publications

References 11 publications

Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal

Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal

Conversion of a microwave synthesized alkali-metal MOF to a carbonaceous anode for Li-ion batteries

Metal Organic Framework Derived MnO2-Carbon Nanotubes for Efficient Oxygen Reduction Reaction and Arsenic Removal from Contaminated Water

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