2019
DOI: 10.1007/s00394-019-01908-7
View full text |Buy / Rent full text
|
Sign up to set email alerts
|

Abstract: Purpose To test the prebiotic activity of wheat arabinogalactan-peptide (AGP), which is a soluble dietary fibre composed of arabinogalactan polysaccharide linked to a 15-residue peptide, which accounts for up to 0.4% of the dry weight of wheat flour. Methods The prebiotic activity of AGP prepared from white wheat flour was tested using in vitro fermentation by colonic bacteria in automated pH-controlled anaerobic stirred batch cultures and compared to fructooligosaccharide (FOS) and wheat flour arabinoxylan (A… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
24
0

Year Published

2019
2019
2020
2020

Publication Types

Select...
3
1

Relationship

2
2

Authors

Journals

citations
Cited by 19 publications
(76 citation statements)
references
References 57 publications
(76 reference statements)
0
24
0
Order By: Relevance
“…AGP is a short (15 amino acid) peptide which is o-glycosylated, probably on three hydroxyproline residues 20 . It accounts for about 0.4% of white flour 21 and is readily fermented by faecal bacteria in vitro 22 , indicating that it may have prebiotic properties in vivo. The concentration shown in Fig.…”
Section: Selection and Genetic Diversity Of Wheat Cultivars A Seriesmentioning
confidence: 99%
“…AGP is a short (15 amino acid) peptide which is o-glycosylated, probably on three hydroxyproline residues 20 . It accounts for about 0.4% of white flour 21 and is readily fermented by faecal bacteria in vitro 22 , indicating that it may have prebiotic properties in vivo. The concentration shown in Fig.…”
Section: Selection and Genetic Diversity Of Wheat Cultivars A Seriesmentioning
confidence: 99%
“…While fructans and galactans are generally accepted as prebiotics, several other fibre types present in wheat including resistant starch, arabinoxylan‐oligosaccharide and arabinogalactan‐peptide have been described as ‘candidate’ prebiotics as these compounds have demonstrated prebiotic potential in vitro or in animal studies and data from human studies is emerging (Damen et al 2012; Lockyer & Nugent 2017; Lockyer & Stanner 2019; Harris et al 2020).…”
Section: Nutrients and Other Bioactives In Bread And Their Associatiomentioning
confidence: 99%
“…In contrast to the present work, the latter study did not include stomach and small intestine digestive processes that can modify peptide profiles prior to their exposure to microbial metabolism. Other reports have shown that wheat arabinogalactan peptides were associated with an increase in SCFAs after 24 h, although this was assessed using in vitro batch fermentation rather than a dynamic GI model system [43]. The multistage dynamic GI model can provide a more accurate representation of human digestive and microbiota metabolism of dietary components as compared to either static digestion models or animal models [49,50].…”
Section: Discussionmentioning
confidence: 99%
“…Two separate digestion runs were completed for each treatment, with a washout/re-stabilization period of 3 days between treatments. Previous in vitro fermentation experiments have also utilized two separate digestion runs [43].…”
Section: Dynamic In Vitro Gastrointestinal Digestion Of Collagen Hydrmentioning
confidence: 99%