volume 32, issue 4, P989-1000 1993
DOI: 10.1021/bi00055a001
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George P. Hess

Abstract: Rapid chemical reaction techniques play an important role in unraveling the mechanism of reactions mediated by soluble proteins, including enzymes involved in the regulation of intracellular processes and the biosynthesis of proteins and nucleic acids. Regulatory proteins change conformation rapidly and must, therefore, be studied in the microsecond-to-millisecond time region. Similar techniques for investigating reactions mediated by membrane-bound neurotransmitter receptors were not available, and the mechan…

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