Determination of residues of malachite green in aquatic animals

Bergwerff, Aldert A.; Scherpenisse, Peter

doi:10.1016/s1570-0232(03)00042-4

Cited by 152 publications

(90 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A number of laboratory based analytical techniques have been developed for determination of malachite green, such as high performance liquid chromatography (HPLC) (Mitrowska et al 2005;Bajc et al 2007;Furusawa 2014;Swarbrick et al 1997;Long et al 2008;Bergwerff et al 2003;Xie et al 2013) and liquid chromatography-tandem mass spectrometry (Nebot et al 2013;Lopez-Gutierrez et al 2013;Hidayah et al 2013). These methods can achieve high sensitivity and excellent accuracy.…”

Section: Introductionmentioning

confidence: 99%

Determination of Malachite Green in Aquaculture Water by Adsorptive Stripping Voltammetry

Zhu

Honeychurch

et al. 2015

Analytical Letters

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Determination of Malachite Green in Aquaculture Water by Adsorptive Stripping Voltammetry

Zhu

Honeychurch

et al. 2015

Analytical Letters

View full text Add to dashboard Cite

“…MG and CV are rapidly metabolised to their non-polar leuco-MG (LMG) and leuco-CV (LCV) forms, which have a longer half-life in fish than the parent compounds [410]. MG is not registered as a veterinary drug and has potential toxicity, teratogenicity and carcinogenicity effects [411]. As a result it is not authorised for use in animals that are produced for human consumption and the EU has set a MRPL of 2 µg kg -1 (sum of MG and LMG) in aquaculture [412].…”

Section: Triphenylmethane Dyesmentioning

confidence: 99%

“…The non-chromophorous leuco analogues are often oxidised to their chromophorous parent compound using PbO2 or other oxidising reagents [414]. It has been reported that MG and LMG are rapidly degraded (most likely through demethylation) during sample preparation [411,415].…”

Section: Triphenylmethane Dyesmentioning

confidence: 99%

Current trends in sample preparation for growth promoter and veterinary drug residue analysis

Kinsella

O’Mahony

Malone

et al. 2009

Journal of Chromatography A

180

View full text Add to dashboard Cite

A comprehensive review is presented on the current trends in sample preparation for isolation of veterinary drugs and growth promotors from foods. The objective of the review is to firstly give an overview of the sample preparation techniques that are applied in field. The review will focus on new techniques and technologies, which improve efficiency and coverage of residues. The underlying theme to the paper is the developments that have been made in multi-residue methods and particularly multi-class methods for residues of licensed animal health products, which have been developed in the last couple of years. The role of multi-class methods is discussed and how they can be accommodated in future residue surveillance.

show abstract

“…This problem has been resolved with either pre-or post-column oxidation of LMG to MG, allowing the total amount of MG residue. [12][13][14][15] However, the oxidation column causes problems including rapid depletion and peak broadening, which lead to decrease in method sensitivity. Recently, detection with mass spectrometric techniques has been proved to be more sensitive and specific than spectroscopic detection.…”

Section: Introductionmentioning

confidence: 99%

Accurate Determination of Malachite Green and Leucomalachite Green in Fish using Isotope Dilution Liquid Chromatography/Mass Spectrometry (ID-LC/MS)

Ahn¹,

Kim²,

Lee³

et al. 2010

Bulletin of the Korean Chemical Society

View full text Add to dashboard Cite

Malachite green (MG) has been used world-widely in aquaculture as a parasiticide or fungicide. Although MG performed successfully, it has not been permitted for use in aquaculture from European Union, USA, and Canada because of its carcinogenicity and mutagenicity. We developed a sensitive and specific method to determine MG and its principal metabolite, leucomalachite green (LMG), respectively by isotope dilution liquid chromatography mass spectrometry (ID-LC/MS). To enhance the extraction recovery of MG and LMG from fish tissue, an additional step, saponification, was introduced in sample preparation process to remove fat in sample extract, which hampered the performance of SPE columns. The residue of MG and LMG in fish was analyzed using liquid chromatography mass spectrometry in the selected ion monitoring (SIM) mode by monitoring at m/z 329 and 334 for MG and d5-MG and at m/z 331 and 337 for LMG and 13 C6-LMG, respectively. This method was validated by comparing with the value of the reference material provided by Laboratory Government Chemistry (LGC). The results agreed within the measurement uncertainty and the accuracy was much improved than the provided reference value by LGC.

show abstract

Determination of residues of malachite green in aquatic animals

Cited by 152 publications

References 10 publications

Determination of Malachite Green in Aquaculture Water by Adsorptive Stripping Voltammetry

Determination of Malachite Green in Aquaculture Water by Adsorptive Stripping Voltammetry

Current trends in sample preparation for growth promoter and veterinary drug residue analysis

Accurate Determination of Malachite Green and Leucomalachite Green in Fish using Isotope Dilution Liquid Chromatography/Mass Spectrometry (ID-LC/MS)

Contact Info

Product

Resources

About