Determination of quercetin in human plasma by HPLC with spectrophotometric or electrochemical detection

Simultaneous Estimation of Quercetin and trans-Resveratrol in Cissus quadrangularis Extract in Rat Serum Using Validated LC-MS/MS Method: Application to Pharmacokinetic and Stability Studies

“…The β-glucuronidase enzyme was used to hydrolyze the glucuronide conjugates of analytes. It is easier to quantify the free form of an analyte, rather than the glucuronide conjugate form [ 36 ].…”

Isoflavones: Chemistry, Analysis, Functions and Effects on Health and Cancer

“…HPLC-ED (electrochemical detection) uses electroactive characteristics of isoflavones. HPLC-ED has better sensitivity than HPLC-UV method since isoflavones contains phenolic groups, which are electroactive (Jones et al, 1998). The assay method is much sensitive for coumestrol, genistein, and daidzein, but baseline stability for detection is problematic although a required an operating electric potential needed to be proper electrical voltage and electrooxidation of impurities present in the mobile phase .…”

Dose-Response Relationships forN7-(2-Hydroxyethyl)Guanine Induced by Low-Dose [14C]Ethylene Oxide: Evidence for a Novel Mechanism of Endogenous Adduct Formation

“…Extracts of HCA-7 cells and rat liver homogenates were prepared based on a published method (31). Typically, 200 mg tissue or 1 Â 10 6 cells were homogenized in 100 AL of acetone/ methanol (1:4).…”