Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2011.12.022 View full text
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Naama Karu, Greg W. Dicinoski, Melissa Hanna-Brown, Paul R. Haddad

Abstract: For the hyphenation of ion chromatography to nebulising detectors or mass spectrometry, suppression of the non-volatile ionic eluent to water is a required step. However, suppression of weakly acidic or weakly basic organic analytes can potentially lead to losses of analytes during suppression resulting from precipitation, hydrophobic adsorption onto the suppressor, or permeation of the analyte through the suppressor membranes. This study investigates the interactions between the suppressor and weak organic ac…

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