Determination of multi-class pesticides residues of cow and human milk samples from Iran using UHPLC-MS/MS and GC-ECD: A probabilistic health risk assessment

Ramezani, Sara; Mahdavi, Vahideh; Gordan, Hasti; Rezadoost, Hasan; Conti, Gea Oliver; Khaneghah, Amin Mousavi

doi:10.1016/j.envres.2022.112730

Cited by 31 publications

(13 citation statements)

References 46 publications

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“…In contrast, the fungicide thiophanate-methyl was detected in four vegetable samples and in six fruit samples as recorded in Tables 1 and 2. As this fungicide is widely used in the control of a variety of pathogens pre-and post-harvest, it was detected in many vegetable and fruit samples [47][48][49][50][51], herbal medicine [52], raisins [45], salmon [53], beebread [54], and also in cow and human milk [55].…”

Section: Discussionmentioning

confidence: 99%

Pesticide Residues in Vegetables and Fruits from Farmer Markets and Associated Dietary Risks

et al. 2022

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The use of pesticides leads to an increase in agricultural production but also causes harmful effects on human health when excessively used. For safe consumption, pesticide residues should be below the maximum residual limits (MRLs). In this study, the residual levels of pesticides in vegetables and fruits collected from farmers’ markets in Sharkia Governorate, Egypt were investigated using LC-MS/MS and GC-MS/MS. A total number of 40 pesticides were detected in the tested vegetable and fruit samples. Insecticides were the highest group in detection frequency with 85% and 69% appearance in vegetables and fruits, respectively. Cucumber and apple samples were found to have the highest number of pesticide residues. The mean residue levels ranged from 7 to 951 µg kg−1 (in vegetable samples) and from 8 to 775 µg kg−1 (in fruit samples). It was found that 35 (40.7%) out of 86 pesticide residues detected in vegetables and 35 (38.9%) out of 90 pesticide residues detected in fruits exceeded MRLs. Results for lambda-cyhalothrin, fipronil, dimothoate, and omethoate in spinach, zucchini, kaki, and strawberry, respectively, can cause acute or chronic risks when consumed at 0.1 and 0.2 kg day−1. Therefore, it is necessary for food safety and security to continuously monitor pesticide residues in fruits and vegetables in markets.

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Section: Discussionmentioning

confidence: 99%

Pesticide Residues in Vegetables and Fruits from Farmer Markets and Associated Dietary Risks

et al. 2022

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“…For decades, LC-MS has found applications in the separation and determination of various contaminants in complex food and environmental matrices [ 32 , 35 , 36 , 37 ]. In this system, as the separated analytes elute from the column, they are introduced into the mass spectrometer, in which they are accelerated through magnetic and electric fields.…”

Section: Chromatographic Techniques For Ep Analysismentioning

confidence: 99%

Recent Advances in the Chromatographic Analysis of Emerging Pollutants in Dairy Milk: A Review (2018–2023)

Ashraf,

Morsi,

Usman

et al. 2024

Molecules

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Emerging pollutants (EPs) encompass natural or synthetic substances found in the environment that pose potential risks, but which have only recently been recognized or monitored. EPs consist of various categories, including pesticides, pharmaceuticals, hormones, mycotoxins, and endocrine-disrupting chemicals (EDCs). Through several pathways, EPs can access food, potentially leading to health impacts when safe concentrations are exceeded. Milk, being a highly nutritious food product that is heavily consumed by many consumers of different ages, is a crucial food matrix where EPs should be regularly monitored. In the literature, a large number of studies have been dedicated to the determination of different EPs in dairy milk, employing different analytical techniques to do so. Chromatography-based techniques are the most prevalent means used for the analysis of EPs in milk, demonstrating significant efficiency, sensitivity, and accuracy for this specific purpose. The extraction of EPs from a complex matrix like milk is essential prior to performing chromatographic analysis. This review comprehensively covers relevant research papers on the extraction and subsequent detection and determination of EPs in milk using chromatographic methods from 2018 to 2023.

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“…Their primary objective is to regulate pesticide application in food commodities, aiming to reduce health risks and environmental impacts associated with pesticide residues. Regional or international standards, known as Maximum Residue Limits (MRLs), have been established by the Codex Alimentarius (CA) and the European Union (EU) for this purpose 1,14,15 . MRLs serve as critical benchmarks, determining the maximum acceptable levels of pesticide residues in various food items.…”

Section: Introductionmentioning

confidence: 99%

Determination and Health Risk Assessment of Carbamate Pesticide Residues in Date Palm fruits (Phoenix dactylifera) Using QuEChERS Method and UHPLC-MS/MS

Morsi,

Ghoudi,

Meetani

2024

Preprint

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This study aimed to investigate carbamate pesticide residues in different varieties of date palm fruits in the UAE, utilizing UHPLC-MS/MS. For sample preparation and clean-up, the efficiency and performance of different QuEChERS dispersive solid-phase extraction kits were compared. Precision and recovery were assessed at 10 𝜇g kg-1 for the three kits, revealing that Kit 2 demonstrated the best performance. The selected QuEChERS method was validated to detect 14 carbamate residues in 55 date samples. The method exhibited strong linearity with R2>0.999 and low LOD (0.01- 0.005 𝜇g kg-1) and LOQ (0.003- 0.04 𝜇g kg-1). Excellent accuracy (recovery: 88-106%) and precision (RSD: 1-11%) were observed, with negligible matrix effect (-4.98-13.26%). All samples contained at least one carbamate residue. While the majority of detected residues were below their MRLs, carbosulfan was found in 21 samples, propoxur in 2 samples, and carbofuran in 1 sample above their MRLs. To assess potential health risks for date consumers, the hazard index (HI) was calculated for carbosulfan, phenmedipham, carbaryl, propoxur, carbofuran, and methomyl. All HI values were below the safety limit of 1.0, indicating that the consumption of dates does not pose a non-carcinogenic health risk for adults and children.

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Determination of multi-class pesticides residues of cow and human milk samples from Iran using UHPLC-MS/MS and GC-ECD: A probabilistic health risk assessment

Cited by 31 publications

References 46 publications

Pesticide Residues in Vegetables and Fruits from Farmer Markets and Associated Dietary Risks

Pesticide Residues in Vegetables and Fruits from Farmer Markets and Associated Dietary Risks

Recent Advances in the Chromatographic Analysis of Emerging Pollutants in Dairy Milk: A Review (2018–2023)

Determination and Health Risk Assessment of Carbamate Pesticide Residues in Date Palm fruits (Phoenix dactylifera) Using QuEChERS Method and UHPLC-MS/MS

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