Determination of insulin levels of the common dormouse (glis glis) and hedgehog (Erinaceus europaeus) with reference to the rat

GPR15–C10ORF99 functional pairing initiates colonic Treg homing in amniotes

“…Another exception is that the C10ORF99 gene was lost in the strictly carnivorous shrew, Sorex araneus , which also lost the colon (Fig EV5 ). According to the divergency time of Sorex araneus (Fig EV5 ), the closest species are Erinaceus europaeus and Tupaia chinensis , which have an intact C10ORF99–GPR15‐signalling pathway and a colon in their digestive system, because both of them kept their omnivorous diet (Castex et al , 1978 ; Yu et al , 2016 ). The sequence of the Sorex araneus GPR15 gene still is intact, although some sensitivity to C10ORF99 has been lost, indicating that Sorex araneus GPR15 is in the process of undergoing inactivation or acquiring alternative functions, due to ligand loss (Fig EV5 ).…”

GPR15–C10ORF99 functional pairing initiates colonic Treg homing in amniotes

“…Another exception is that the C10ORF99 gene was lost in the strictly carnivorous shrew, Sorex araneus , which also lost the colon (Fig EV5 ). According to the divergency time of Sorex araneus (Fig EV5 ), the closest species are Erinaceus europaeus and Tupaia chinensis , which have an intact C10ORF99–GPR15‐signalling pathway and a colon in their digestive system, because both of them kept their omnivorous diet (Castex et al , 1978 ; Yu et al , 2016 ). The sequence of the Sorex araneus GPR15 gene still is intact, although some sensitivity to C10ORF99 has been lost, indicating that Sorex araneus GPR15 is in the process of undergoing inactivation or acquiring alternative functions, due to ligand loss (Fig EV5 ).…”

GPR15–C10ORF99 functional pairing initiates colonic Treg homing in amniotes

“…Another exception is that the C10ORF99 gene was lost in the strictly carnivorous shrew, Sorex araneus , which also lost the colon (Fig EV5 ). According to the divergency time of Sorex araneus (Fig EV5 ), the closest species are Erinaceus europaeus and Tupaia chinensis , which have an intact C10ORF99–GPR15‐signalling pathway and a colon in their digestive system, because both of them kept their omnivorous diet (Castex et al , 1978 ; Yu et al , 2016 ). The sequence of the Sorex araneus GPR15 gene still is intact, although some sensitivity to C10ORF99 has been lost, indicating that Sorex araneus GPR15 is in the process of undergoing inactivation or acquiring alternative functions, due to ligand loss (Fig EV5 ).…”

GPR15–C10ORF99 functional pairing initiates colonic Treg homing in amniotes

“…Another exception is that the C10ORF99 gene was lost in the strictly carnivorous shrew, Sorex araneus , which also lost the colon (Fig EV5 ). According to the divergency time of Sorex araneus (Fig EV5 ), the closest species are Erinaceus europaeus and Tupaia chinensis , which have an intact C10ORF99–GPR15‐signalling pathway and a colon in their digestive system, because both of them kept their omnivorous diet (Castex et al , 1978 ; Yu et al , 2016 ). The sequence of the Sorex araneus GPR15 gene still is intact, although some sensitivity to C10ORF99 has been lost, indicating that Sorex araneus GPR15 is in the process of undergoing inactivation or acquiring alternative functions, due to ligand loss (Fig EV5 ).…”