Determinants of uptake of a third dose of SARS-CoV-2 vaccines in patients with inflammatory bowel disease

COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP): a multicentre, prospective, case-control study

“…[6][7][8] In some countries, including the UK, immunosuppressed patients have been prioritised for third primary doses and booster doses of vaccine, 9 and in the UK, uptake of third doses amongst immunosuppressed patients with IBD has been reported at 79%. 10 Data about immunity following third vaccine doses in patients with IBD are limited, and interpretation is problematic due to a lack of healthy control participants or data about cellmediated immunity. 11 We have shown that a two-dose schedule of mRNA vaccine is associated with higher anti-SARS-CoV-2 spike antibody binding than two doses of adenovirus vector vaccine in the immunosuppressed population with IBD.…”

COVID-19 Immunization Rates in Patients with Inflammatory Bowel Disease Worldwide: A Systematic Review and Meta-Analysis

“…Regarding age, the available evidence suggests that older individuals display greater adherence to vaccination [25][26][27][28][30][31][32]35]. This inclination can be attributed to the increased susceptibility of advanced age to COVID-19 complications, which is frequently accompanied by an increased prevalence of other underlying health conditions.…”

“…Regarding gender, greater levels of compliance were noted among females [26,28,35], and various studies [25][26][27][28][30][31][32]35] indicated reduced hesitancy among older individuals. Social determinants have also emerged as significant factors.…”

“…Furthermore, two studies were excluded due to the unavailability of the full text. As a result, 13 studies were considered eligible and met the inclusion criteria [24][25][26][27][28][29][30][31][32][33][34][35][36] (Table 1), while 111 studies were excluded for not meeting the specified criteria. Two studies were from the US, two from China, two from the UK, two from Italy, one from Poland, one from Denmark, one from Canada, one from Australia, and one from Kuwait (Table 1, Figure 2).…”

“…Social determinants have also emerged as significant factors. Not being part of an ethnic minority [26,28,31], having a higher economic status [27,31], and residing in an urban area [27,28] are linked to enhanced vaccine compliance.…”