Determinants of pancreaticoenteric anastomotic leak following pancreaticoduodenectomy

Srivastava, Smriti; Sikora, Sadiq S.; Pandey, Chandra Kant; Kumar, Ashok; Saxena, Rajan

doi:10.1046/j.1440-1622.2001.02184.x

Cited by 43 publications

(31 citation statements)

References 34 publications

(66 reference statements)

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“…Pancreatic anastomotic leak remains the leading cause of morbidity with an incidence reaching 20% even in specialized centers [13–17]. Complicated pancreatic anastomotic leak may lead to sepsis and hemorrhage with a mortality rate of up to 40% [8, 13, 14, 18].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pancreatic Anastomosis Disruption Seven Years Postpancreaticoduodenectomy

Faraj

Zahr

Mukherji

et al. 2010

Case Reports in Medicine

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We are reporting a case of a 22 year-old female patient, who underwent a pancreaticoduodenectomy previously for a solid-pseudopapillary neoplasm of the pancreas and was re-admitted seven years later with a pancreatic leak following disruption of the pancreatico-jejunal anastomosis. Exploratory laparotomy revealed a large collection at the level of the pancreatic anastomosis with major disruption of the pancreatico-jejunal anastomosis. The pancreatic stump was refreshed as well as the jejunal site and a duct to mucosa anastomosis was performed. She remains well with a follow up of 18 months.

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Section: Discussionmentioning

confidence: 99%

“…The perioperative factors which predispose to pancreatic leak include older age (more than 65 years), preoperative jaundice [4], large intraoperative blood loss [20], intraoperative blood transfusion, prolonged operative time (>8 hrs), diabetes [17], low patient volume per surgeon, and ampullary or duodenal disease [21]. …”

Section: Discussionmentioning

confidence: 99%

Pancreatic Anastomosis Disruption Seven Years Postpancreaticoduodenectomy

Faraj

Zahr

Mukherji

et al. 2010

Case Reports in Medicine

View full text Add to dashboard Cite

show abstract

“…Pancreatic anastomotic leak remains the leading cause of morbidity with an incidence reaching 20% even in specialized centers [13][14][15][16][17]. Complicated pancreatic anastomotic leak may lead to sepsis and hemorrhage with a mortality rate of up to 40% [8,13,14,18].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pancreatic Anastomosis Disruption Seven Years Post Pancreaticoduodenectomy

Faraj

Zaher

Khalifeh

2010

Journal of Surgical Research

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We are reporting a case of a 22 year-old female patient, who underwent a pancreaticoduodenectomy previously for a solidpseudopapillary neoplasm of the pancreas and was re-admitted seven years later with a pancreatic leak following disruption of the pancreatico-jejunal anastomosis. Exploratory laparotomy revealed a large collection at the level of the pancreatic anastomosis with major disruption of the pancreatico-jejunal anastomosis. The pancreatic stump was refreshed as well as the jejunal site and a duct to mucosa anastomosis was performed. She remains well with a follow up of 18 months.

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“…European studies advocate the routine use of octreotide, while North American trials conclude that octreotide is useless. [14][15][16][17][18][19][38][39][40][41] In our study, we used octreotide as a prophylactic measure in high-risk patients when the pancreas was found to be soft with a small (<3 mm) duct. Octreotide was started intraoperatively when these findings were noted as a continuous drip of 10 μg/h.…”

Section: Discussionmentioning

confidence: 99%