Determinants of health-related quality of life in patients with chronic obstructive pulmonary disease.

Ketelaars, Corry A.J.; Schlosser, M.; Mostert, R.; Abu‐Saad, Huda Huijer; Halfens, Ruud J.G.; Wouters, Emiel F.M.

doi:10.1136/thx.51.1.39

Cited by 192 publications

(147 citation statements)

References 27 publications

(1 reference statement)

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“…A relationship between the SGRQ total score and FEV 1, which is in agreement with several other studies, (5,(19)(20)(21)(22) was observed in this study. Our results did not show a relationship between body composition attributes and HRQoL.…”

Section: Discussionsupporting

confidence: 82%

Influência do sistema de fornecimento de oxigênio na qualidade de vida de pacientes com hipoxemia crônica

et al. 2007

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Objective: To evaluate the health-related quality of life of patients with chronic obstructive pulmonary disease receiving long-term oxygen therapy (LTOT) at home through oxygen cylinders and compare these results with those obtained six months after the transition from oxygen cylinders to oxygen concentrators. Methods: A total of 45 patients were evaluated. Of those, 24 had chronic hypoxemia and 21 presented no evidence of hypoxemia. The patients with chronic hypoxemia had been regularly receiving LTOT for at least the last six months and were evaluated at baseline, while using cylinders, and six months after the transition from cylinders to concentrators. The non-hypoxemic patients were evaluated at the same time points as were the hypoxemic patients. In order to evaluate quality of life, a version of the Saint George's Respiratory Questionnaire (SGRQ), translated and validated for use in Brazil, was administered. Results: At baseline, quality of life, as evaluated using the total score and the symptom and impact domain scores of the SGRQ, was more impaired in the hypoxemic patients than in the non-hypoxemic patients. After six months of using the concentrators, the hypoxemic patients presented a significant improvement in the quality of life, and, at that time, no difference was found between the patients with and without hypoxemia. Conclusion: Our findings show that quality of life is impaired in patients with chronic obstructive pulmonary disease and chronic hypoxemia, that their quality of life can be improved through regular use of LTOT, and that the oxygen delivery system has an influence on this improvement.Keywords: Pulmonary disease, Chronic obstructive; Anoxemia; Oxygen inhalation therapy; Quality of life. ResumoObjetivo: Avaliar a qualidade de vida relacionada à saúde de pacientes com doença obstrutiva crônica das vias aéreas recebendo oxigenoretapia domiciliar prolongada (ODP) por meio de cilindros de oxigênio e comparar estes resultados com os obtidos após seis meses de modificação do sistema de fornecimento para concentradores de oxigênio. Métodos: Um total de 45 pacientes, 24 com hipoxemia crônica e 21 sem evidências de hipoxemia, foram avaliados. Os pacientes com hipoxemia crônica estavam recebendo ODP regularmente durante pelo menos os últimos seis meses e foram avaliados no momento basal, em uso de cilindro, e após seis meses de transição para concentradores. Os pacientes não hipoxêmicos foram avaliados no mesmo intervalo de tempo que os pacientes hipoxêmicos. Para avaliar a qualidade de vida foi utilizada a versão validada para língua portuguesa (Brasil) do Questionário Respiratório Saint George (Saint George's Respiratory Questionnaire -SGRQ). Resultados: No momento inicial, os pacientes hipoxêmicos apresentaram maior comprometimento da qualidade de vida, avaliada pelo escore total e pelos escores dos domínios sintomas e impacto do SGRQ, que os pacientes não hipoxêmicos. Após seis meses, houve melhora significativa da qualidade de vida dos pacientes hipoxêmicos e, neste momento, não...

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Section: Discussionsupporting

confidence: 82%

Influência do sistema de fornecimento de oxigênio na qualidade de vida de pacientes com hipoxemia crônica

et al. 2007

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“…For example, Schrier, Dekker, Kaptein, and Dijkman (1990) found that elderly patients with CNSLD experienced substantial problems in the area of physical as well as psychological functioning and reported more dysfunction compared to a healthy control group. In accordance with other studies (e.g., Guyatt, Townsend, Berman, & Pugsley, 1987;Ketelaars et al, 1996;McSweeny, Grant, Heaton, Adams, & Timms, 1982;Williams & Bury, 1989), Okubadejo, Jones, and Wedzicha (1996) recently reported impairment in most areas of health status in patients with chronic obstructive pulmonary disease (COPD). However, gender differences have been given very little attention.…”

Section: Introductionsupporting

confidence: 78%

Gender Differences in Sarcoidosis: Symptoms, Quality of Life, and Medical Consumption

2000

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ABSTRACT. The aim of this study was to examine gender differences in quality of life (QOL) and in constitutional symptoms that coincide with sarcoidosis. The study population included 1026 sarcoidosis patients--all members of the Dutch Sarcoidosis Society--who completed the WHOQOL-100 and a symptom checklist. Women experienced more symptoms than men. With regard to QOL, male and female patients who suffered from symptoms differed in the broader domains of Physical Health and Psychological Health. Specific facets reflected pain, sleep, positive affect, appearance, mobility, and activities of daily living. Future studies should focus on the different experience of the disease between male and female patients more extensively. Studies are needed to evaluate whether the differences in the present study between male and female sarcoidosis patients are caused by a subject selection bias or life style differences; have a genetic, hormonal or biological base; or just are an epiphenomenon.

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“…It is well established that in patients with COPD, the relationship between their physiological impairments and their health status measurements is generally weak (28,29). However, the correlation was generally lower with the French-Canadian questionnaires than reported in previous studies with the original English CRQ (7,30) and SGRQ (8,31). This rather poor correlation of the French-Canadian translated questionnaires and FEV 1 may be explained by the manner in which patients were selected and the type of intervention under study.…”

Section: Discussioncontrasting

confidence: 49%

French‐Canadian Version of the Chronic Respiratory and of the St George′s Respiratory Questionnaires: An Assessment of their Psychometric Properties in Patients with Chronic Obstructive Pulmonary Disease

Bourbeau

Maltais

Rouleau

et al. 2004

Canadian Respiratory Journal

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BACKGROUND: French versions of the Chronic Respiratory Questionnaire (CRQ) and the St George's Respiratory Questionnaire (SGRQ) have largely been used in Canada, although the process by which they were translated remains unknown and the psychometric properties of these translated versions have not been assessed in a properly designed study. OBJECTIVE: To translate and evaluate the psychometric properties of the French-Canadian versions of the CRQ and the SGRQ. METHODS: The questionnaires were translated according to standardized guidelines for cross-cultural adaptation. Measurements were made at baseline and again after two weeks in 27 chronic obstructive pulomonary disease (COPD) patients known to have stable disease. Measurements were also taken pre-and post-treatment in patients with acute exacerbation of COPD (33 patients) or in pulmonary rehabilitation (32 patients). RESULTS:The CRQ showed high test-retest reliability (the majority above 0.70), although it was slightly lower for the dyspnea dimension (0.58 to 0.65). The SGRQ also showed high test-retest reliability (above 0.80), although it was lower for the symptoms dimension (0.54 to 0.58). The internal consistency reliability coefficients ranged from 0.73 to 0.90 for the CRQ and above 0.80 for the SGRQ, except for the symptoms dimension. The Pearson's correlation coefficients were low (less than 0.30) between most of the translated questionnaire dimension scores and forced expiratory volume in 1 s, 6 min walking test and dyspnea measures. The correlation was generally high (greater than 0.50) between the two questionnaires and the 36-item short form health survey, and for those domains that measured the same construct. The changes in the total and subscale scores of the CRQ and the SGRQ (except for the symptoms domain) were all largely above the variability of the score in the stable disease group. CONCLUSION: The present study confirms that the FrenchCanadian translated versions of the CRQ and the SGRQ perform well with respect to their psychometric properties. They are both suitable for their intended purpose, ie, to detect change in health status in patients with COPD when assessing if a treatment is beneficial. However, the symptoms domain of the SGRQ cannot be used to assess acute change with respect to a given therapy. RÉSULTATS : Le CRQ a montré une bonne fiabilité de test-retest (audessus de 0,70 dans la plupart des cas), même si celle-ci était légèrement inférieure (0,58-0,65) à l'égard de la dyspnée. Le SGRQ a aussi montré une bonne fiabilité de test-retest (au-dessus de 0,80), même si celle-ci était légèrement inférieure (0,54-0,58) à l'égard des symptômes. Les coefficients de cohérence interne variaient entre 0,73 et 0,90 pour le CRQ et ils se tenaient au-dessus de 0,80 pour le SGRQ, sauf en ce qui concerne les symptômes. Les coefficients de corrélation de Bravais-Pearson étaient faibles (inférieurs à 0,30) entre la plupart des résultats des différents aspects dans les questionnaires traduits et le volume expiratoire maximal par seconde, l'ép...

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Determinants of health-related quality of life in patients with chronic obstructive pulmonary disease.

Cited by 192 publications

References 27 publications

Influência do sistema de fornecimento de oxigênio na qualidade de vida de pacientes com hipoxemia crônica

Influência do sistema de fornecimento de oxigênio na qualidade de vida de pacientes com hipoxemia crônica

Gender Differences in Sarcoidosis: Symptoms, Quality of Life, and Medical Consumption

French‐Canadian Version of the Chronic Respiratory and of the St George′s Respiratory Questionnaires: An Assessment of their Psychometric Properties in Patients with Chronic Obstructive Pulmonary Disease

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