Determinantes da qualidade de vida na doença de Paget óssea

Castro, Gláucio Ricardo Werner de; Castro, Silvania Ana Fernandes de; Pereira, Ivânio Alves; Zimmermann, Adriana Fontes; Toscano, Maria Amazile; Neves, Fabrício Souza; Scottini, Maria Aparecida; Paupitz, Juliane Aline; Rosa, Júlia Salvan da; Buss, Ziliani da Silva; Fröde, Tânia Sílvia

doi:10.1016/j.rbr.2017.04.005

Cited by 1 publication

(2 citation statements)

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“…Segundo Castro et al (2017), em um estudo realizado com 50 pacientes os resultados da pontuação total do SF-36 e seus domínios, saúde física e saúde mental, se correlacionaram significativamente com a dor óssea e deformidades. O estado civil se correlacionou significativamente com a pontuação total do SF-36 e com seu domínio da saúde mental.…”

Section: Marcadores Utilizados Para O Diagnóstico E Acompanhamento La...unclassified

“…Segundo Castro et al (2017), a probabilidade de o paciente ter um bom prognóstico sobe consideravelmente, quanto mais cedo for descoberto e iniciado o tratamento. Entretanto, segundo o Protocolo Clínico e Diretrizes Terapêuticas da Doença de Paget Óssea do Ministério da Saúde, o acompanhamento médico através de exames laboratoriais e por imagem de pacientes com DPO, devem ser realizados por toda a vida do paciente.…”

Section: Introductionunclassified

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Laboratory and Imaging follow-up of the patient with Boné Paget´s

Andrade

Júnior

Neto

et al. 2023

RSD

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Paget's Disease of Bone (POD) has a viral and/or hereditary etiology, its strong familial component is noticeable, since 40% of patients have a family history of the disease, strengthening the idea that there is an autosomal dominant inheritance pattern. The main follow-up method used for patients with POP is the measurement of serum alkaline phosphatase, which is also used to assess the initial response to treatment. The purpose of this bibliographical study is to present, synthesize and describe the most relevant aspects that guide the medical follow-up of patients diagnosed with Paget's Disease of Bone, in order to cite and analyze the importance of medical action in the care of these patients, in an attempt to generate knowledge and updates that help in dealing with these patients, above all, to avoid the evolution of the disease and the appearance of possible complications. UpToDate, Scielo, Virtual Health Library (VHL), PubMed and ebscohost were used as databases, using the following descriptors: Paget's disease, laboratory monitoring, imaging tests, genetics and complications. The pagetic patient can evolve with osteosarcoma, irreversible hearing loss and paraplegia, making its multidisciplinary follow-up essential, through serum and bone alkaline phosphatase dosages, as well as the use of imaging tests, such as scintigraphy and radiography, for research of structural complications or neoplastic transformations, aiming at symptomatic relief along with delaying the progression of the disease, avoiding the total disability of the patient.

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Section: Marcadores Utilizados Para O Diagnóstico E Acompanhamento La...unclassified

Section: Introductionunclassified