Detection of Varicella Zoster Virus DNA and Viral Antigen in the Late Stage of Bilateral Acute Retinal Necrosis Syndrome

Polymerase chain reaction as a rapid diagnostic tool for therapy of acute retinal necrosis syndrome

“…Most ARN syndrome cases are believed to result from secondary reactivation of a latent infection [Duker and Blumenkranz, 1991]. In this patient the development of bilateral and nonsynchronous ARN may be due to blood-borne dissemination of an endogenous virus (from sensory ganglia) or re-exposure to exogenous VZV (active herpes zoster skin lesions), as suggested by Rummelt et al [1992].…”

Polymerase chain reaction as a rapid diagnostic tool for therapy of acute retinal necrosis syndrome

“…Most ARN syndrome cases are believed to result from secondary reactivation of a latent infection [Duker and Blumenkranz, 1991]. In this patient the development of bilateral and nonsynchronous ARN may be due to blood-borne dissemination of an endogenous virus (from sensory ganglia) or re-exposure to exogenous VZV (active herpes zoster skin lesions), as suggested by Rummelt et al [1992].…”

Acute Retinal Necrosis with Choroidal Inflammation, Optic Perineuritis, and Early Retinal Detachment: A Case Report

“…Pathologically, choroidal involvement in ARN is suggested to result from lymphocytic infiltration, diffuse plasma cell infiltration, macrophagic and lymphocytic stromal infiltrates, and perivascular cuffing, leading to marked choroidal thickening, often up to three times normal thickness. Complete sequential involvement of the choriocapillaris has also been documented [ 7 , 10 , 11 ]. Choroidal involvement has been associated with a higher risk of accelerated retinal damage and contributes to early RRD, as observed in our patient [ 6 ].…”

Polymerase Chain Reaction Evaluation of Infectious Multifocal Serpiginoid Choroiditis

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Polymerase chain reaction as a rapid diagnostic tool for therapy of acute retinal necrosis syndrome

“…Most ARN syndrome cases are believed to result from secondary reactivation of a latent infection [Duker and Blumenkranz, 1991]. In this patient the development of bilateral and nonsynchronous ARN may be due to blood-borne dissemination of an endogenous virus (from sensory ganglia) or re-exposure to exogenous VZV (active herpes zoster skin lesions), as suggested by Rummelt et al [1992].…”

Acute Retinal Necrosis with Choroidal Inflammation, Optic Perineuritis, and Early Retinal Detachment: A Case Report

“…Pathologically, choroidal involvement in ARN is suggested to result from lymphocytic infiltration, diffuse plasma cell infiltration, macrophagic and lymphocytic stromal infiltrates, and perivascular cuffing, leading to marked choroidal thickening, often up to three times normal thickness. Complete sequential involvement of the choriocapillaris has also been documented [ 7 , 10 , 11 ]. Choroidal involvement has been associated with a higher risk of accelerated retinal damage and contributes to early RRD, as observed in our patient [ 6 ].…”

Polymerase Chain Reaction Evaluation of Infectious Multifocal Serpiginoid Choroiditis

“……”

Polymerase chain reaction as a rapid diagnostic tool for therapy of acute retinal necrosis syndrome

“…Most ARN syndrome cases are believed to result from secondary reactivation of a latent infection [Duker and Blumenkranz, 1991]. In this patient the development of bilateral and nonsynchronous ARN may be due to blood-borne dissemination of an endogenous virus (from sensory ganglia) or re-exposure to exogenous VZV (active herpes zoster skin lesions), as suggested by Rummelt et al [1992].…”

Acute Retinal Necrosis with Choroidal Inflammation, Optic Perineuritis, and Early Retinal Detachment: A Case Report

“…Pathologically, choroidal involvement in ARN is suggested to result from lymphocytic infiltration, diffuse plasma cell infiltration, macrophagic and lymphocytic stromal infiltrates, and perivascular cuffing, leading to marked choroidal thickening, often up to three times normal thickness. Complete sequential involvement of the choriocapillaris has also been documented [ 7 , 10 , 11 ]. Choroidal involvement has been associated with a higher risk of accelerated retinal damage and contributes to early RRD, as observed in our patient [ 6 ].…”

Polymerase Chain Reaction Evaluation of Infectious Multifocal Serpiginoid Choroiditis

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