Detection of human papillomavirus DNA in squamous cell carcinoma of the nail bed and finger determined by polymerase chain reaction

Immunohistochemical detection of p53 protein in cutaneous lesions from transplant recipients harbouring human papillomavirus DNA

“…However, more than 70 HPV types have been described and we can not exclude that other types than those that we tested might infect cutaneous lesions from transplant recipients. The detection of mucosal HPV types 6, 11, 16 and 18 which was previously described in few cases of skin lesions from the general population [2,15,28], was a common feature in our grafted patients [37]. HPV type 5, commonly found in skin cancers from patients with epidermodysplasia verruciformis [43], has also been previously found in grafted patient skin lesions [3,36,42].…”

Primary Malignant Tumors of the Nail Unit

“…36 More than 60% of cases of nail unit squamous cell carcinoma contain HPV-16 DNA by polymerase chain reaction and dot blot hybridization. 29,31 Other reports have demonstrated identical HPV strains in periungual and genital verrucae with atypical and bowenoid changes in the same patient. 37 the nail bed and reviewed the literature, showing a disproportionate number of neoplasms on the second, third, and fourth fingers.…”

“…Several reports have investigated the role of HPV and nail unit squamous cell carcinoma. [29][30][31][32] HPV types 16 and 18 are known to trigger mucosal squamous dysplasia in cervical 33 and anogenital 34 lesions, and HPV has been implicated in the cutaneous squamous cell carcinomas in renal allograft patients. 35 In addition, HPV of different types (particularly HPV-5) may trigger squamous cell carcinoma in patients with epidermodysplasia verruciformis.…”

Nail Unit Tumors: A Study of 234 Patients in the Dermatology Department of the “Dr Manuel Gea González” General Hospital in Mexico City

“…The etiology of the SCC of the nail apparatus is unknown but it has been associated with the presence of human papillomavirus (HPV). 23,24 One study that took place in our department demonstrated the presence of the HPV in five of nine patients with SCC of the nail apparatus and the more frequent types were 16, 19, 6, and 7 (unpublished personal experience). All of our cases were observed in the fingers and none in the toes.…”