Detection of early abnormalities of left ventricular function by hemodynamic, echo-tissue Doppler imaging, and mitral Doppler flow techniques in patients with coronary artery disease and normal ejection fraction

Bolognesi, R; Tsialtas, Dimitri; Barilli, Angela Luciana; Manca, C; Zeppellini, R; Javernaro, Antonio; Cucchini, F

doi:10.1067/mje.2001.113234

Cited by 77 publications

(49 citation statements)

References 24 publications

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“…The rate of contraction, +dP/dt, was also significantly lower compared with Ang II-treated Tgfb1 +/+ Rag1 -/-mice (P < 0.05). The echocardiographic and hemodynamic indices of contractility did not correlate in this study; however, this finding was similar to other experimental and clinical studies comparing echocardiographic and catheterization analyses (42)(43)(44)(45).…”

Section: Resultssupporting

confidence: 88%

TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

Schultz¹,

Witt²,

Glascock³

et al. 2002

J. Clin. Invest.

216

125

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Section: Resultssupporting

confidence: 88%

TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

Schultz¹,

Witt²,

Glascock³

et al. 2002

J. Clin. Invest.

216

125

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“…Thus, GRS measurements might be less accurate and show greater variability. Another reason may be that radial systolic function changes later than longitudinal systolic function in cardiac ischemia [23].…”

Section: Discussionmentioning

confidence: 99%

Maternal cardiac remodeling and dysfunction in preeclampsia: a three-dimensional speckle-tracking echocardiography study

Cong

Fan

Yang

et al. 2015

Int J Cardiovasc Imaging

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Aims preeclampsia (PE) is a pregnancy complication that remains a main cause of maternal morbidity and mortality. The aims of this study were to investigate left ventricle (LV) performance in PE and to compare maternal cardiac function between early-onset preeclampsia (EP) and late-onset preeclampsia (LP) by novel threedimensional (3D) speckle-tracking echocardiography (STE) parameters while considering LV loading and shape. Methods and Results Two-dimensional echocardiography and 3D STE were performed in 43 women with EP, 41 women with LP, and 81 normal pregnancies. Global longitudinal strain (GLS), global circumferential strain (GCS), global area strain (GAS), and global radial strain (GRS) were measured using 3D speckle-tracking software. There was eccentric hypertrophy and reduced LV ejection fraction (EF) in PE; meanwhile, GLS in EP and LP, GCS in LP, as well as GAS and GRS in EP significantly decreased in PE versus controls. All 3D strain indices were correlated with gestation age. Increased left atrial (LA) volume index was detected in PE. Higher LV mass index and lower 3D-derived strain value were present in women with EP compared to that in women with LP. Conclusion PE cases exhibited significant eccentric hypertrophy, ventricular dysfunction, and LA remodeling. Furthermore, myocardial deformation abnormalities preceded chamber dysfunction in this hypertensive disorder complicated pregnancy. Compared with LP, women with EP demonstrated more remarkable cardiac damage.

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“…The systolic diameter reduction in the LV short axis is considered to be caused by the contraction of circumferentially oriented fibers, whereas MAPSE has been shown to be the result of the contraction of longitudinally oriented fibers. This is observed in patients with diastolic dysfunction in whom the long-axis function of the left ventricle measured by MAPSE or SmLV is already impaired while the radial function assessed by LVEF can be still preserved [22,23]. In our study, MAPSE was more useful than SmLV to detect LV diastolic and systolic dysfunction in patients with CKD.…”

Section: Discussionmentioning

confidence: 50%

Echocardiographic Changes in Patients with Stage 3-5 Chronic Kidney Disease and Left Ventricular Diastolic Dysfunction

Gromadziński

Pruszczyk

2014

Cardiorenal Med

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Background: Left ventricular (LV) diastolic dysfunction in chronic kidney disease (CKD) patients frequently leads to the development of congestive heart failure. We evaluated changes in echocardiographic parameters among CKD patients with LV diastolic dysfunction. Methods: We examined 70 ambulatory patients with CKD at stages 3-5 and 26 patients without CKD as a control group. Standard echocardiography and tissue Doppler imaging were performed on all patients. Patients with CKD were divided into two groups according to the results of lateral mitral early diastolic velocity (EmLV_lat): a group with diastolic dysfunction (DD group; EmLV_lat <8 cm/s) and a group without diastolic dysfunction (WDD group; EmLV_lat ≥8 cm/s). Results: Compared to the patients in the WDD group, those in the DD group were characterized by lower values of mitral annular plane systolic excursion [MAPSE; 13 (11-17) vs. 14 (11-16) mm, p < 0.0001] and lateral mitral annular systolic velocity [SmLV_lat; 7 (5-14) vs. 8 (5-13) cm/s, p = 0.006]. The area under the receiver operating characteristic (ROC) curve of the MAPSE level for the detection of LV diastolic dysfunction was 0.801 [95% CI 0.684-0.890, p < 0.0001], whereas a ROC-derived MAPSE value of ≤13 mm was characterized by a sensitivity of 84.4% and a specificity of 75.8% for diagnosing LV diastolic dysfunction. The only independent variable predicting LV diastolic dysfunction was MAPSE [OR = 0.39; 95% CI 0.21-0.74, p = 0.003]. Conclusion: We showed that reduced MAPSE, but not SmLV_lat, is an independent predictive factor for LV diastolic dysfunction in CKD patients.

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Detection of early abnormalities of left ventricular function by hemodynamic, echo-tissue Doppler imaging, and mitral Doppler flow techniques in patients with coronary artery disease and normal ejection fraction

Cited by 77 publications

References 24 publications

TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

Maternal cardiac remodeling and dysfunction in preeclampsia: a three-dimensional speckle-tracking echocardiography study

Echocardiographic Changes in Patients with Stage 3-5 Chronic Kidney Disease and Left Ventricular Diastolic Dysfunction

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